Results 51 to 60 of about 665,456 (302)

Cross-talk between two nucleotide-signaling pathways in Staphylococcus aureus. [PDF]

, 2014
Nucleotide-signaling pathways are found in all kingdoms of life and are utilized to coordinate a rapid response to external stimuli. The stringent response alarmones guanosine tetra- (ppGpp) and pentaphosphate (pppGpp) control a global response allowing ...
Alexandra R. Willis, An, Angelika Gründling, Bae, Bai, Bai, Battesti, Boles, Cashel, Cashel, Charpentier, Corrigan, Corrigan, Corrigan, Cosgrove, Dalebroux, Fiil, Fong, French, Gao, Gao, Geiger, Geiger, Geiger, Gentry, Glass, Griffiths, Gründling, Hanahan, Herbert, Horsburgh, Knutsson Jenvert, Lee, Lemos, Lisa Bowman, Lu, Lund, Luo, L̸eski, Maisonneuve, McDonough, Mehne, Memmi, Miller, Mwangi, Nagarajan, Nanamiya, Nelson, Nguyen, Ochi, Potrykus, Pozzi, Rallu, Rao, Rebecca M. Corrigan, Roelofs, Rudin, Römling, Smith, Song, Sureka, Thomaides, Volkhard Kaever, Webb, Witney, Witte, Woodward   +66 more
core   +1 more source

Nitrofurantoin Prompts the Stringent Response in Bacillus subtilis [PDF]

Microbiology, 1981
Nitrofurantoin causes the stringent response in Bacillus subtilis. After exposure of a stringent strain to this drug, the intracellular concentrations of guanosine 3'-diphosphate 5'-diphosphate (ppGpp), guanosine 3'-diphosphate 5'-triphosphate (pppGpp) and ATP increased, while that of GTP decreased.
J M, Lopez, P, Fortnagel
openaire   +2 more sources

(p)ppGpp: Magic Modulators of Bacterial Physiology and Metabolism

Frontiers in Microbiology, 2020
When bacteria experience growth-limiting environmental conditions, the synthesis of the hyperphosphorylated guanosine derivatives (p)ppGpp is induced by enzymes of the RelA/SpoT homology (RSH)-type protein family. High levels of (p)ppGpp induce a process
Wieland Steinchen, Victor Zegarra, Gert Bange   +2 more
doaj   +1 more source

A new Skyrme interaction with improved spin-isospin properties [PDF]

, 2012
A correct determination of the spin-isospin properties of the nuclear effective interaction should lead, among other improvements, to an accurate description of the Gamow-Teller Resonance (GTR).
G. Colò, H. Sagawa, P. R. Bevington, X. Roca-Maza   +3 more
core   +2 more sources

(p)ppGpp and CodY Promote Enterococcus faecalis Virulence in a Murine Model of Catheter-Associated Urinary Tract Infection

mSphere, 2019
In Firmicutes, the nutrient-sensing regulators (p)ppGpp, the effector molecule of the stringent response, and CodY work in tandem to maintain bacterial fitness during infection. Here, we tested (p)ppGpp and codY mutant strains of Enterococcus faecalis in
C. Colomer-Winter, A. L. Flores-Mireles, S. Kundra, S. J. Hultgren, J. A. Lemos   +4 more
doaj   +1 more source

Gut microbes modulate (p)ppGpp during a time-restricted feeding regimen

mBio, 2023
Mammals exhibit daily fasting and feeding patterns that produce a fluctuating environment in the gut. By colonizing germfree mice with Bacteroides thetaiotaomicron and examining gene expression through a time-restricted feeding cycle, we demonstrate that
Amy Ontai-Brenning, Randy Hamchand, Jason M. Crawford, Andrew L. Goodman   +3 more
doaj   +1 more source

Role of (p)ppGpp in Viability and Biofilm Formation of Actinobacillus pleuropneumoniae S8. [PDF]

, 2015
Actinobacillus pleuropneumoniae is a Gram-negative bacterium and the cause of porcine pleuropneumonia. When the bacterium encounters nutritional starvation, the relA-dependent (p)ppGpp-mediated stringent response is activated.
Bossé, JT, Langford, PR, Li, G, Wang, C, Xie, F, Zhang, Y   +5 more
core   +3 more sources

Nitrogen stress response and stringent response are coupled in Escherichia coli [PDF]

Nature Communications, 2014
Abstract Assimilation of nitrogen is an essential process in bacteria. The nitrogen regulation stress response is an adaptive mechanism used by nitrogen-starved Escherichia coli to scavenge for alternative nitrogen sources and requires the global transcriptional regulator ...
Brown, DR, Barton, G, Pan, Z, Buck, M, Wigneshweraraj, S   +4 more
openaire   +4 more sources

Pressure-driven flow of solid helium

, 2006
The recent torsional oscillator results of Kim and Chan suggest a supersolid phase transition in solid 4He. We have used a piezoelectrically driven diaphragm to study the flow of solid helium through an array of capillaries.
A. F. Andreev, G. Bonfait, James Day, John Beamish, T. Kobayashi   +4 more
core   +1 more source

The stringent response and cell cycle arrest in Escherichia coli. [PDF]

PLoS Genetics, 2008
The bacterial stringent response, triggered by nutritional deprivation, causes an accumulation of the signaling nucleotides pppGpp and ppGpp. We characterize the replication arrest that occurs during the stringent response in Escherichia coli.
Daniel J Ferullo, Susan T Lovett
doaj   +1 more source