Results 31 to 40 of about 207,701 (143)
(p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in
mBio, 2020 The facultative intracellular pathogen Listeria monocytogenes, like many related Firmicutes, uses the nucleotide second messenger cyclic di-AMP (c-di-AMP) to adapt to changes in nutrient availability, osmotic stress, and the presence of cell wall-acting ...
Bret N. Peterson +8 more
doaj +1 more source
Microbial Primer: What is the stringent response and how does it allow bacteria to survive stress? [PDF]
Microbiology (United Kingdom)Rebecca Corrigan
exaly +2 more sources
Tolerance and Persistence to Drugs: A Main Challenge in the Fight Against Mycobacterium tuberculosis
Frontiers in Microbiology, 2020 The treatment of tuberculosis is extremely long. One of the reasons why Mycobacterium tuberculosis elimination from the organism takes so long is that in particular environmental conditions it can become tolerant to drugs and/or develop persisters able ...
Francesca Boldrin +4 more
doaj +1 more source
Phenotypic heterogeneity in mycobacterial stringent response [PDF]
BMC Systems Biology, 2011 Abstract Background A common survival strategy of microorganisms subjected to stress involves the generation of phenotypic heterogeneity in the isogenic microbial population enabling a subset of the population to survive under stress. In a recent study, a mycobacterial population of M.
Sayantari Ghosh +5 more
openaire +4 more sources
Clinical rel mutations in Staphylococcus aureus prime pathogen expansion under nutrient stress
mSphere, 2023 Persistent infection by Staphylococcus aureus has been linked to the bacterial stringent response (SR), a conserved stress response pathway regulated by the Rel protein.
Edwin Chen +6 more
doaj +1 more source
Classic Spotlight: Studies of the Stringent Response [PDF]
Journal of Bacteriology, 2016 The views expressed in this Editorial do not necessarily reflect the views of the journal or of ASM. Early investigators of bacterial metabolism felt that the major activities of the cell must be balanced so that every component of the cell could be duplicated in the same time interval.
Richard L. Gourse, Sean Crosson
openaire +2 more sources
Microbiology Spectrum, 2023 In natural environments, nutrients are usually scarce, causing microorganisms to grow slowly while staying metabolically active. These natural conditions can be simulated using retentostat cultivations.
Angela Rocio Ortiz Camargo +6 more
doaj +1 more source
Mutation of rpoB Shifts the Nutrient Threshold Triggering Myxococcus Multicellular Development
Frontiers in Microbiology, 2022 The ability to perceive and respond to environmental change is essential to all organisms. In response to nutrient depletion, cells of the soil-dwelling δ-proteobacterium Myxococcus xanthus undergo collective morphogenesis into multicellular fruiting ...
Sabrina A. Eisner +2 more
doaj +1 more source
RelQ Mediates the Expression of β-Lactam Resistance in Methicillin-Resistant Staphylococcus aureus
Frontiers in Microbiology, 2019 An induced stringent response, which is established by an increased level of (p)ppGpp, is required for the expression of β-lactam resistance in methicillin-resistant Staphylococcus aureus (MRSA).
Ajita Bhawini +6 more
doaj +1 more source
Metabolites, 2012 Metabolite profiling of E. coli W3110 and the isogenic DrelA mutant cells was used to characterize the RelA-dependent stringent control of metabolism under different growth conditions.
Sónia Carneiro +3 more
doaj +1 more source