Results 31 to 40 of about 212,665 (269)

Mutation of rpoB Shifts the Nutrient Threshold Triggering Myxococcus Multicellular Development

Frontiers in Microbiology, 2022
The ability to perceive and respond to environmental change is essential to all organisms. In response to nutrient depletion, cells of the soil-dwelling δ-proteobacterium Myxococcus xanthus undergo collective morphogenesis into multicellular fruiting ...
Sabrina A. Eisner, Gregory J. Velicer, Yuen-Tsu N. Yu   +2 more
doaj   +1 more source

The opposite effects of stringent response on phage infection of <i>Pseudomonas putida</i>. [PDF]

Microlife
Autorite ORCID: Alicja Cecylia Lewańcyk https://orcid.org/0009-0001-4600-2277 Mariliis Hinnu https://orcid.org/0000-0002-6096-0658 Elise Mägi https://orcid.org/0009-0006-8703-8475 Roger Rikberg https://orcid.org/0009-0002-0293-3819 Age Brauer https ...
Lewańczyk AC, Hinnu M, Mägi E, Rikberg R, Brauer A, Tamman H.   +5 more
europepmc   +2 more sources

Orphan Toxin OrtT (YdcX) of Escherichia coli Reduces Growth during the Stringent Response

Toxins, 2015
Toxin/antitoxin (TA) systems are nearly universal in prokaryotes; toxins are paired with antitoxins which inactivate them until the toxins are utilized. Here we explore whether toxins may function alone; i.e., whether a toxin which lacks a corresponding ...
Sabina Islam, Michael J. Benedik, Thomas K. Wood   +2 more
doaj   +1 more source

RelQ Mediates the Expression of β-Lactam Resistance in Methicillin-Resistant Staphylococcus aureus

Frontiers in Microbiology, 2019
An induced stringent response, which is established by an increased level of (p)ppGpp, is required for the expression of β-lactam resistance in methicillin-resistant Staphylococcus aureus (MRSA).
Ajita Bhawini, Parul Pandey, Ashutosh Prakash Dubey, Aafreen Zehra, Gopal Nath, Mukti Nath Mishra, Mukti Nath Mishra   +6 more
doaj   +1 more source

Codon-Dependent Transcriptional Changes in Response to Tryptophan Limitation in the Tryptophan Auxotrophic Pathogens Chlamydia trachomatis and Streptococcus pyogenes

mSystems, 2021
Chlamydia trachomatis and Streptococcus pyogenes are among the most prevalent bacterial pathogens of humans. Interestingly, both pathogens are tryptophan (Trp) auxotrophs and must acquire this essential amino acid from their environment.
Scot P. Ouellette, Nathan D. Hatch, Nicholas A. Wood, Andrea L. Herrera, Michael S. Chaussee   +4 more
doaj   +1 more source

Influence of the RelA Activity on E. coli Metabolism by Metabolite Profiling of Glucose-Limited Chemostat Cultures

Metabolites, 2012
Metabolite profiling of E. coli W3110 and the isogenic DrelA mutant cells was used to characterize the RelA-dependent stringent control of metabolism under different growth conditions.
Sónia Carneiro, Silas G. Villas-Bôas, Eugénio C. Ferreira, Isabel Rocha   +3 more
doaj   +1 more source

Physiology and Transcriptional Analysis of (p)ppGpp-Related Regulatory Effects in Corynebacterium glutamicum

Frontiers in Microbiology, 2019
The alarmone species ppGpp and pppGpp are elementary components of bacterial physiology as they both coordinate the bacterial stress response and serve as fine-tuners of general metabolism during conditions of balanced growth.
Matthias Ruwe, Marcus Persicke, Tobias Busche, Benjamin Müller, Jörn Kalinowski   +4 more
doaj   +1 more source

Identification of a RelA/SpoT Homolog and Its Possible Role in the Accumulation of Astaxanthin in Haematococcus pluvialis

Frontiers in Plant Science, 2022
A RelA/SpoT homolog, HpRSH, was identified in Haematococcus pluvialis. HpRSH was found to catalyze Mg2+-dependent guanosine tetraphosphate (ppGpp) synthesis and Mn2+-dependent ppGpp hydrolysis, respectively.
Hui Jin, Hui Jin, Yong Min Lao, Jin Zhou, Zhong Hua Cai   +4 more
doaj   +1 more source

Phenotypic and Functional Characterization of Human Memory T Cell Responses to Burkholderia pseudomallei [PDF]

, 2009
Copyright: © 2009 Tippayawat et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and ...
Direk Limmathurotsakul, Suwannasaen, D, Sharon J Peacock, Ganjana Lertmemongkolchai, Titball, Richard W., Helen S Atkins, Tippayawat, Patcharaporn, Richard W Titball, Saenwongsa, Wipawee, Duangchan Suwannasaen, Chetchotisakd, Ploenchan, Chetchotisakd, P, Wipawee Saenwongsa, Jirawan Mahawantung, Philip L Felgner, Bancroft, Gregory J., Saenwongsa, W, Titball, RW, Atkins, Helen S, Mahawantung, J, Limmathurotsakul, Direk, Peacock, Sharon J., Limmathurotsakul, D, Mahawantung, Jirawan, Gregory J Bancroft, Suwannasaen, Duangchan, Peacock, SJ, Tippayawat, P, Atkins, HS, Titball, Richard W, Felgner, Philip L., Lertmemongkolchai, Ganjana, Felgner, Philip L, Ploenchan Chetchotisakd, Felgner, PL, Bancroft, GJ, Atkins, Helen S., Lertmemongkolchai, G, Bancroft, Gregory J, Peacock, Sharon J, Patcharaporn Tippayawat   +40 more
core   +1 more source

A role for the stringent response in ciprofloxacin resistance in Pseudomonas aeruginosa. [PDF]

Sci Rep
AbstractPseudomonas aeruginosa is a major cause of nosocomial infections and the leading cause of chronic lung infections in cystic fibrosis and chronic obstructive pulmonary disease patients. Antibiotic treatment remains challenging because P. aeruginosa is resistant to high concentrations of antibiotics and has a remarkable ability to acquire ...
García-Villada L, Degtyareva NP, Brooks AM, Goldberg JB, Doetsch PW.   +4 more
europepmc   +4 more sources