Results 51 to 60 of about 207,701 (143)
Nitrogen stress response and stringent response are coupled in Escherichia coli [PDF]
Nature Communications, 2014 Abstract Assimilation of nitrogen is an essential process in bacteria. The nitrogen regulation stress response is an adaptive mechanism used by nitrogen-starved Escherichia coli to scavenge for alternative nitrogen sources and requires the global transcriptional regulator ...
Brown, DR +4 more
openaire +3 more sources
mSphere, 2019 In Firmicutes, the nutrient-sensing regulators (p)ppGpp, the effector molecule of the stringent response, and CodY work in tandem to maintain bacterial fitness during infection. Here, we tested (p)ppGpp and codY mutant strains of Enterococcus faecalis in
C. Colomer-Winter +4 more
doaj +1 more source
Gut microbes modulate (p)ppGpp during a time-restricted feeding regimen
mBio, 2023 Mammals exhibit daily fasting and feeding patterns that produce a fluctuating environment in the gut. By colonizing germfree mice with Bacteroides thetaiotaomicron and examining gene expression through a time-restricted feeding cycle, we demonstrate that
Amy Ontai-Brenning +3 more
doaj +1 more source
The stringent response and cell cycle arrest in Escherichia coli. [PDF]
PLoS Genetics, 2008 The bacterial stringent response, triggered by nutritional deprivation, causes an accumulation of the signaling nucleotides pppGpp and ppGpp. We characterize the replication arrest that occurs during the stringent response in Escherichia coli.
Daniel J Ferullo, Susan T Lovett
doaj +1 more source
Understanding housing market responses to stringent energy codes
Real Estate Economics, 2023 AbstractIncreased energy efficiency in buildings is essential to reducing carbon emissions and addressing climate change. Massachusetts' Green Communities Act of 2008, aiming for a 50% reduction in carbon emissions by 2030 and net‐zero by 2050, mandates the Stretch Energy Code for eligibility for state funding.
Maria Jimena Muzio +3 more
openaire +1 more source
Phage portal proteins counteract stringent-response–mediated restriction
Nature CommunicationsBacteria restrict viral replication not only through dedicated defense systems but also by entering physiological states that limit cellular resources, yet how phages overcome such host-imposed barriers remains unclear.
Kristina Kronborg +4 more
doaj +1 more source
Rel is required for morphogenesis of resting cells in Mycobacterium smegmatis
Frontiers in Microbiology, 2016 Recently we showed that upon transfer of growing Mycobacterium smegmatis into saline, the bacilli exited the canonical cell division cycle and formed septated multi-nucleoided cells. Under shock starvation (i.e.
Mu-Lu Wu, Chuu Ling Chan, Thomas Dick
doaj +1 more source
Stringent Response Regulation of Biofilm Formation in Vibrio cholerae [PDF]
Journal of Bacteriology, 2012 ABSTRACT Biofilm formation is a key factor in Vibrio cholerae environmental survival and host colonization. Production of biofilm enables V. cholerae to survive and persist in aquatic environments and aids in the passage through the gastric acid barrier to allow access to the small ...
Huajun, He +3 more
openaire +2 more sources
Global transcriptional analysis of the stringent response in Enterococcus faecalis [PDF]
Microbiology, 2012 In Enterococcus faecalis, production of guanosine tetraphosphate/guanosine pentaphosphate [(p)ppGpp], the effector molecule of the stringent response, is controlled by the bifunctional synthetase/hydrolase RelA and the monofunctional synthetase RelQ. Previously, the (p)ppGpp profiles of strains lacking relA, relQ or both genes indicated that RelA is ...
Anthony O, Gaca +3 more
openaire +2 more sources
Bio-Protocol, 2016 The stringent response in bacteria is a stress response that is mediated by the signaling molecules guanosine tetraphosphate and pentaphosphate [(p)ppGpp], alarmones that are also directly related to virulence. Therefore, determination of (p)ppGpp levels
Smitha Sivapragasam, Anne Grove
doaj +1 more source