Results 41 to 50 of about 313,405 (294)

What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands [PDF]

, 2019
Dipeptidyl peptidase 4 (DPP4) is an exopeptidase found either on cell surfaces where it is highly regulated in terms of its expression and surface availability (CD26) or in a free/circulating soluble constitutively available and intrinsically active form.
Aguilar-Pérez, Alexandra, Awad, Mohamed E., Eisa, Nada H., Elmansi, Ahmed M., Fulzele, Sadanand, Hamrick, Mark W., Herberg, Samuel, Hill, William D., Hussein, Khaled A., Isales, Carlos M., Kondrikov, Dmitry, McGee-Lawrence, Meghan E., Periyasamy-Thandavan, Sudharsan, Volkman, Brian F.   +13 more
core   +1 more source

Sphingosine 1-phosphate receptor 1 is required for MMP-2 function in bone marrow mesenchymal stromal cells: implications for cytoskeleton assembly and proliferation [PDF]

, 2018
Bone marrow-derived mesenchymal stromal cell- (BM-MSC-) based therapy is a promising option for regenerative medicine. An important role in the control of the processes influencing the BM-MSC therapeutic efficacy, namely, extracellular matrix remodelling
Anderloni, Giulia, Chellini, Flaminia, Frati, Alessia, Matteini, Francesca, Meacci, Elisabetta, Nosi, Daniele, Pierucci, Federica, Sassoli, Chiara, Tani, Alessia, Vestri, Ambra, Zecchi-Orlandini, Sandra   +10 more
core   +7 more sources

Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties [PDF]

, 2019
Heterogeneous populations of human bone marrow-derived stromal cells (BMSC) are among the most frequently tested cellular therapeutics for treating degenerative and immune disorders, which occur predominantly in the aging population.
Andrzejewska, Anastazja, Beez, Christien, Blankenstein, Antje, Catar, Rusan, Duda, Georg, Geissler, Sven, Jacobi, Dorit, Jürchott, Karsten, Kamhieh-Milz, Julian, Krüger, David, Krüger, Ulrike, Moll, Guido, Qazi, Taimoor Hasan, Reinke, Petra, Reinke, Simon, Richter, Sarina, Sass, Frauke Andrea, Schlickeiser, Stephan, Schoon, Janosch, Souidi, Naima, Streitz, Mathias, Strunk, Dirk, Zemojtel, Tomasz   +22 more
core   +1 more source

Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy [PDF]

, 2020
Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine. A large number of studies have shown the beneficial effects of MSC-based therapies to treat different pathologies, including neurological disorders ...
Capilla González, Vivian, Gauthier, Benoit R., Hmadcha, Abdelkrim, Martín Montalvo, Alejandro, Soria Escoms, Bernat   +4 more
core   +1 more source

Stromal-cell-derived Factor 1-α Promotes Tumor Progression in Colorectal Cancer [PDF]

Journal of the Korean Society of Coloproctology, 2012
Although stromal-cell-derived factor (SDF)-1α is suggested to be involved in tumorigenicity and tumor angiogenesis, the clinicopathological significance of its expression in colorectal cancers is not fully understood. We examined SDF-1α expression in colorectal cancers and investigated its relationship to clinicopathological features such as tumor ...
Park, Se Jun, Ahn, Tae Sung, Cho, Sung Woo, Kim, Chang Jin, Jung, Dong Jun, Son, Myung Won, Bae, Sang Ho, Shin, Eung Jin, Lee, Moon Soo, Kim, Chang Ho, Baek, Moo Jun   +10 more
openaire   +2 more sources

Platelet-derived stromal cell-derived factor-1 is required for the transformation of circulating monocytes into multipotential cells. [PDF]

PLoS ONE, 2013
BACKGROUND: We previously described a primitive cell population derived from human circulating CD14(+) monocytes, named monocyte-derived multipotential cells (MOMCs), which are capable of differentiating into mesenchymal and endothelial lineages.
Noriyuki Seta, Yuka Okazaki, Hiroshi Miyazaki, Takashi Kato, Masataka Kuwana   +4 more
doaj   +1 more source

Stromal Cell-Derived Factor-1 Antagonizes Slit/Robo SignalingIn Vivo [PDF]

The Journal of Neuroscience, 2007
Retinal ganglion cell axons exit the eye, enter the optic stalk, cross the ventral midline at the optic chiasm, and terminate in the optic tectum of the zebrafish. While in the optic stalk, they grow immediately adjacent to cells expressing the powerful retinal axon repellent slit2. The chemokine stromal cell-derived factor-1 (SDF1) is expressed within
Sreekanth H, Chalasani, Angela, Sabol, Hong, Xu, Michael A, Gyda, Kendall, Rasband, Michael, Granato, Chi-Bin, Chien, Jonathan A, Raper   +7 more
openaire   +2 more sources

Role of SDF-1/CXCR4 in cancer-associated fibroblasts [PDF]

Jichu yixue yu linchuang, 2020
Cancer-associated fibroblasts (CAFs), important component of tumor microenvironment, secrete a variety of factors that play an important role in the occurrence and development of malignant tumors. Stromal cell derived factor-1(SDF-1) secreted by CAFs and
YU Biao, LIU Qing, WU Xiao-ming
doaj  

Axonal growth arrests after an increased accumulation of Schwann cells expressing senescence markers and stromal cells in acellular nerve allografts [PDF]

, 2016
Acellular nerve allografts (ANAs) and other nerve constructs do not reliably facilitate axonal regeneration across long defects (>3 cm). Causes for this deficiency are poorly understood.
Ee, Xueping, Hoben, Gwendolyn M, Hunter, Daniel A, Mackinnon, Susan E, Moore, Amy M, Pan, Deng, Poppler, Louis H, Schellhardt, Lauren, Snyder-Warwick, Alison K, Stewart, Sheila A, Wood, Matthew D, Yan, Ying   +11 more
core   +2 more sources

Stromal cell-derived factor: pathological and clinical potentialities [PDF]

РМЖ. Мать и дитя, 2020
O.V. Prokhorova1, A.A. Olina2, G.Kh. Tolibova2, T.G. Tral’2 1Ural State Medical University, Yekaterinburg, Russian Federation 2D.O. Ott Research Institute of Obstetrics, Gynecology & Reproduction, St.
O.V. Prokhorova, A.A. Olina, G.Kh. Tolibova, T.G. Tral   +3 more
doaj