Mesenchymal Differentiation and Organ Distribution of Established Human Stromal Cell Lines in NOD/SCID Mice [PDF]
Two human stromal cell lines were established previously from bone marrow-derived primary long-term cultures by immortalization using the SV40 large T antigen and cellular cloning. After irradiation, the fibroblast-like cell lines L87/4 and L88/5 support
Thalmeier, Karin +6 more
core +1 more source
Stromal Cell-Derived Factor-1 Promotes Cell Migration, Tumor Growth of Colorectal Metastasis
In a mouse model of established extrahepatic colorectal metastasis, we analyzed whether stromal cellderived factor (SDF) 1 stimulates tumor cell migration in vitro, angiogenesis, tumor growth in vivo.
Otto Kollmar +6 more
doaj +1 more source
Adipose-derived mesenchymal stromal/stem cells : tissue localization, characterization, and heterogeneity [PDF]
Adipose tissue as a stem cell source is ubiquitously available and has several advantages compared to other sources. It is easily accessible in large quantities with minimal invasive harvesting procedure, and isolation of adipose-derived mesenchymal ...
Helmut Geiger +3 more
core +1 more source
Stromal Cell-Derived Factor 1 Mediates Immune Cell Attraction upon Urinary Tract Infection
Urinary tract infection (UTI) is the most common type of bacterial infection in humans. Fifty percent of all women will experience at least one UTI in their lifetime, with uropathogenic Escherichia coli (UPEC) accounting for 80% of reported cases.
Batya Isaacson +6 more
doaj +1 more source
Increased immunoreactivity of stromal cell-derived factor‐1 and angiogenesis in asthma [PDF]
Stromal cell-derived factor‐1 (SDF‐1) acts as a chemoattractant for leukocytes and can induce neovascularisation. To examine the role of SDF‐1 in the development of angiogenesis, immunohistochemical studies were performed on bronchial biopsy specimens from asthmatic and control subjects.Bronchial biopsy specimens were obtained from 13 asthmatic and ...
M, Hoshino +4 more
openaire +2 more sources
SDF1 Gene Variation Is Associated with Circulating SDF1 alpha Level and Endothelial Progenitor Cell Number-The Bruneck Study [PDF]
BACKGROUND: Stromal cell-derived factor-1 (SDF1) and its receptor CXC chemokine receptor 4 (CXCR4) play a critical role in progenitor cell homing, mobilization and differentiation.
Marjan Jahangiri +31 more
core +2 more sources
C-X-C chemokine receptor type 4 and stromal cell–derived factor-1 were proven to play important roles in several types of cancer and in many biological processes connected with tumor growth, invasion, angiogenesis, and metastasis.
Yao-ping Li +6 more
doaj +1 more source
TGF beta 1 attenuates expression of prolactin and IGFBP-1 in decidualized endometrial stromal cells by both SMAD-dependent and SMAD-independent pathways [PDF]
Background: Decidualization (differentiation) of the endometrial stromal cells during the secretory phase of the menstrual cycle is essential for successful implantation.
Jones Marius +30 more
core +1 more source
Stromal cell-derived factor 1 regulates the actin organization of chondrocytes and chondrocyte hypertrophy. [PDF]
Stromal cell-derived factor 1 (SDF-1/CXCL12/PBSF) plays important roles in the biological and physiological functions of haematopoietic and mesenchymal stem cells.
Koichi Murata +12 more
doaj +1 more source
Generation of human adult mesenchymal stromal/stem cells expressing defined xenogenic vascular endothelial growth factor levels by optimized transduction and flow cytometry purification [PDF]
Adult mesenchymal stromal/stem cells (MSCs) are a valuable source of multipotent progenitors for tissue engineering and regenerative medicine, but may require to be genetically modified to widen their efficacy in therapeutic applications.
Melly, L. +26 more
core +1 more source

