Stromal Derived Factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis
Renal cell carcinoma (RCC) is characterized by organ-specific metastases. The chemokine stromal derived factor-1 (SDF-1/CXCL12) and its receptor CXCR4 have been suggested to regulate organ-specific metastasis in various other cancers.
Reckamp Karen +7 more
doaj +1 more source
Cell lineage specific distribution of H3K27 trimethylation accumulation in an in vitro model for human implantation [PDF]
Female mammals inactivate one of their two X-chromosomes to compensate for the difference in gene-dosage with males that have just one X-chromosome. X-chromosome inactivation is initiated by the expression of the non-coding RNA Xist, which coats the X ...
Weimar, Charlotte H. E. +34 more
core +1 more source
Stromal Cell-Derived Factor-1 Retention and Cardioprotection for Ischemic Myocardium [PDF]
Background— Stromal cell-derived factor-1 (SDF-1) is a chemoattractant of stem/progenitor cells, and several studies have shown that SDF-1 may improve ventricular function after infarction. SDF-1 is cleaved by proteases including matrix metalloproteinase-2 (MMP-2) and CD26/dipeptidylpeptidase-4 (DPP-4), which are activated in ...
Sachiko, Kanki +7 more
openaire +2 more sources
SDF-1 and its receptor in the ventricles of rat with monocrotaline-induced pulmonary hypertension
Aim: Chemokine stromal cell derived factor-1 (SDF-1) plays an important role in many processes such as apoptosis, proliferation, migration and angiogenesis, and these effects are mediated mostly by the receptor CXCR4.
Veteskova J. +7 more
doaj +1 more source
Background and objectives Evidence on the associations between baseline stromal cell-derived factor (SDF)-1 and clinical outcomes in acute ischemic stroke patients is lacking.
Shoujiang You +11 more
doaj +1 more source
Background and Objective: Exercise in cardiac patients after coronary artery bypass grafting (CABG) improves cardiovascular function by increasing the capillary density of the myocardium.
Seyed Hadi Seyedi +4 more
doaj
Oxygen tension plays a critical role in the hematopoietic microenvironment in vitro
Background In the bone marrow mesenchymal stromal cells and osteoblasts form functional niches for hematopoietic stem and progenitor cells. This microenvironment can be partially mimicked using in vitro co-culture systems.
Duohui Jing +5 more
doaj +1 more source
Inflammatory events drive neural stem cell migration by elevating stromal-derived factor 1 alpha
Background: Ischemic stroke is the most common cause of ischemia-related death globally. Brain injuries due to stroke and trauma are typically followed by inflammation reactions within the central nervous system (CNS).
Ziyun Jiang, Mingliang Tang
doaj +1 more source
Stromal Cell-Derived Factor-1 as a Chemoattractant for Follicular Center Lymphoma B Cells [PDF]
Follicular center lymphoma displays widespread lymph node involvement at diagnosis. The chemoattractants that control the locomotion of follicular center lymphoma B cells have not been established. Stromal cell-derived factor-1 (SDF-1) is a CXC-class chemokine that enhances the migration of normal human B cells and is expressed in peripheral lymphoid ...
CORCIONE A +10 more
openaire +5 more sources
Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin [PDF]
Pathological processes involved in the initiation of rheumatoid synovitis remain unclear. We undertook the present study to identify immune and stromal processes that are present soon after the clinical onset of rheumatoid arthritis ( RA) by assessing a ...
Lee, CY +28 more
core +1 more source

