Results 101 to 110 of about 76,107 (347)

Sequencing of human identification markers in an Uyghur population using the MiSeq FGxTM Forensic Genomics System

Forensic Sciences Research, 2020
Massively parallel sequencing (MPS) offers a useful alternative to capillary electrophoresis (CE) based analysis of human identification markers in forensic genetics.
Halimureti Simayijiang, Niels Morling, Claus Børsting   +2 more
doaj   +1 more source

Identification, characterization and forensic application of novel Y-STRs [PDF]

, 2005
Y-chromosomal polymorphic STRs are a powerful tool for forensic and evolutionary studies. Within the last decade, a series of Y-STR systems have been developed and demonstrated to be suitable for a variety of forensic applications including sexual ...
IIDA, Reiko, KISHI, Koichiro
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Copy Number Variations in Short Tandem Repeats Modulate Growth Traits in Penaeid Shrimp Through Neighboring Gene Regulation

Animals
Penaeid shrimp, with its genomes enriched in short tandem repeats (STRs), presents an ideal model for studying the distribution and biological functions of STRs.
Hao Zhou, Guangfeng Qiang, Yan Xia, Jian Tan, Qiang Fu, Kun Luo, Xianhong Meng, Baolong Chen, Meijia Chen, Juan Sui, Ping Dai, Xupeng Li, Mianyu Liu, Qun Xing, Jie Kong, Sheng Luan   +15 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Genome-wide detection of short tandem repeat expansions by long-read sequencing

BMC Bioinformatics, 2020
Background Short tandem repeat (STR), or “microsatellite”, is a tract of DNA in which a specific motif (typically 
Qian Liu, Yao Tong, Kai Wang
doaj   +1 more source

First mutation rate analysis Of 24 autosomal STRs in Argentina

, 2019
We investigate the mutation rates of autosomal STRs in paternity tests including trios or duos, in our laboratory, along a period of ten years. We analyzed 5986 parent-child meiosis including 24 autosomal STRs, corresponded into the expanded CODIS core ...
Sala, Adriana Andrea, Corach, Daniel, Caputo, Mariela   +2 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

STRS SpaceWire FPGA Module

, 2011
An FPGA module leverages the previous work from Goddard Space Flight Center (GSFC) relating to NASA s Space Telecommunications Radio System (STRS) project.
Lux, James P., Lang, Minh, Stern, Ryan A., Taylor, Gregory H.   +3 more
core