Results 81 to 90 of about 1,183,105 (286)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Embedding Principal Component Analysis for Data Reductionin Structural Health Monitoring on Low-Cost IoT Gateways [PDF]

open access: yes, 2019
Principal component analysis (PCA) is a powerful data reductionmethod for Structural Health Monitoring. However, its computa-tional cost and data memory footprint pose a significant challengewhen PCA has to run on limited capability embedded platformsin ...
Abdelgawad A.   +8 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

A Miniaturized and Ultra-Low-Power Wireless Multi-Parameter Monitoring System with Self-Powered Ability for Aircraft Smart Skin

open access: yesSensors
The aircraft smart skin (ASS) with structural health monitoring capabilities is a promising technology. It enables the real-time acquisition of the aircraft’s structural health status and service environment, thereby improving the performance of the ...
Chongqi Wang, Yu Wang, Wei Pu, Lei Qiu
doaj   +1 more source

Detecting the Presence of High Water-to-Cement Ratio in Concrete Surfaces Using Highly Nonlinear Solitary Waves

open access: yesApplied Sciences, 2016
We describe a nondestructive evaluation (NDE) method based on the propagation of highly nonlinear solitary waves (HNSWs) to determine the excess of water on the surface of existing concrete structures.
Piervincenzo Rizzo   +3 more
doaj   +1 more source

Development of a robust structural health monitoring system for wind turbine foundations [PDF]

open access: yes, 2012
The construction of onshore wind turbines has rapidly been increasing as the UK attempts to meet its renewable energy targets. As the UK’s future energy depends more on wind farms, safety and security are critical to the success of this renewable energy ...
Currie, Magnus   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Performance testing of a low power consumption wireless sensor communication system integrated with an energy harvesting power source [PDF]

open access: yes, 2012
This paper presents the performance testing results of a wireless sensor communication system with low power consumption integrated with a vibration energy harvesting power source.
Giuliano, Alessandro   +4 more
core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

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