Results 111 to 120 of about 2,448,479 (335)

Automatic detection of complex structural genome variation across world populations [PDF]

, 2017
Bo Zhou, Joseph G. Arthur, Hanmin Guo, Chris Hughes, Taeyoung Kim, Yi‐Ling Huang, Reenal Pattni, HoJoon Lee, Hanlee P. Ji, Giltae Song, Dean Palejev, Xiang Zhu, Wing Hung Wong, Alexander E. Urban   +13 more
openalex   +1 more source

Structural Variation of BRD4-BD1 Complexes [PDF]

, 2021
Ellen Guest, Stephen D. Pickett, Jonathan D. Hirst   +2 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

On the nature of the (de)coupling of the magnetostructural transition in Er$_5$Si$_4$

, 2017
In this report, a successful thermodynamical model was employed to understand the structural transition in Er$_5$Si$_4$, able to explain the decoupling of the magnetic and structural transition.
Algarabel, Pedro A., Amaral, João S., Araújo, João P., Barbosa, Marcelo B., Belo, João H., Costa, Rui M., Fortunato, Nuno M., Gonçalves, João N., Ibarra, Manuel R., Magén, César, Morellon, Luis, Pereira, André M.   +11 more
core   +1 more source

Evolutionary dynamics and functional characterization of Jasmonate ZIM-domain (JAZ) genes across Camellia sinensis pan-genome

Beverage Plant Research
Jasmonate ZIM-domain (JAZ) proteins regulate critical processes in plants, including growth, development, secondary metabolism, and responses to biotic and abiotic stresses.
Biao Xiong, Yongyi Yang, Qingqing Li, Suzhen Niu   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Structural Variations Associated with Adaptation and Coat Color in Qinghai‐Tibetan Plateau Cattle

Advanced Science
Structural variations (SVs) play crucial roles in the evolutionary adaptation of domesticated animals to natural and human‐controlled environments, but SVs have not been explored in Tibetan cattle, which recently migrated and rapidly adapted to the high ...
Xiaoting Xia, Fuwen Wang, Xiaoyu Luo, Shuang Li, Yang Lyu, Yining Zheng, Zhijie Ma, Kaixing Qu, Rende Song, Jianyong Liu, Jicai Zhang, Basang Wangdui, Basang Zhuzha, Suolang Quji, Li Zhao, Silang Wangmu, Ciren Luobu, Nima Cangjue, Danzeng Luosang, Suolang Sizhu, Haijian Cheng, Ruizhe Li, Zhipeng Wu, Ruihua Dang, Yongzhen Huang, Xianyong Lan, Luohao Xu, Haifei Hu, WaiYee Low, Zhuqing Zheng, Yu Wang, Yuanpeng Gao, Lu Deng, Johannes A. Lenstra, Jianlin Han, Xueyi Yang, Wenfa Lyu, Bizhi Huang, Chuzhao Lei, Ningbo Chen   +39 more
doaj   +1 more source

Data from: Chromosome-scale reference genome and RAD-based genetic map of yellow starthistle (Centaurea solstitialis) reveal putative structural variation and QTLs associated with invader traits

, 2022
Bryan Reatini, F. Alice Cang, Qiuyu Jiang, Michael T. W. McKibben, Michael S. Barker, Loren H. Rieseberg, Katrina M. Dlugosch   +6 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Structural Variation in the Nasal Bone Region of European Moose (Alces Alces L.) [PDF]

, 1990
Kristian Nygren, S. Paatsama, B. de Gritz   +2 more
openalex   +1 more source