Results 191 to 200 of about 2,448,479 (335)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Structural variation drives enhancer hijacking via 3D genome disruption in ccRCC. [PDF]

NPJ Digit Med
Dong Y, Xia W, Yang Z, Ren L, Wang H, Zhou Y, Li Q, Chen Z, Xia Z, Zheng Y, Wang F, He N, Cheng B, Ma D, Shao W, Guo W, Wang S, Liu Z, Shen J, Qi Y, Gong X, Jin J, Xie B, Zhu G, Zhang C.   +24 more
europepmc   +1 more source

Characterization of DeNovo Structural Variations Induced by TALENs Targeting hDMD in Mouse ES Cells using TSSV

, 2013
Seyed Yahya Anvar
openalex   +1 more source

Synthesis of ZnO/Al:ZnO nanomaterial: structural and band gap variation in ZnO nanomaterial by Al doping [PDF]

, 2012
Muhammad Nafees, Wasim Liaqut, Salamat Ali, Muhammad Ahsan Shafique   +3 more
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Comparative mitochondrial genome analysis of Panax ginseng reveals structural variation and genetic diversity. [PDF]

Sci Rep
Xi Y, Liao X, Hu H, Guo S, Shang W, Liu S, Yang TJ, Chen S, Xu J, Dou D.   +9 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

The Landscape of Structural Variation in Aye-Ayes (Daubentonia madagascariensis). [PDF]

Genome Biol Evol
Versoza CJ, Jensen JD, Pfeifer SP.
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

cuteSV-OL: a real-time structural variation detection framework for nanopore sequencing devices. [PDF]

Bioinformatics
Guo W, Liu Y, Wang Y, Jiang T.
europepmc   +1 more source