Results 31 to 40 of about 646,180 (295)
Frontiers in Cell and Developmental Biology, 2022 Background: Structural variations (SVs) are common genetic alterations in the human genome that could cause different phenotypes and diseases, including cancer.
Taobo Hu +24 more
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Biology, 2023 The Chinese soft-shelled turtle (Pelodiscus sinensis) is an important aquaculture reptile with rich nutritional and medicinal values. In recent decades, the wild resources of P. sinensis have been depleting due to natural and artificial factors.
Jing Chen +8 more
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Understanding genome structural variations
Oncotarget, 2015 Genome structural variations (SVs) in the human genome are defined as DNA sequence polymorphisms of at least a few dozen or few hundred bases in length and include deletions, duplications, inversions, translocation, retroelement insertions, and more complex rearrangements that could be thought of as consisting of multiple fragments from the just listed
Alexej Abyzov, Shantao Li, Mark Gerstein
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Human Pangenomics: Promises and Challenges of a Distributed Genomic Reference
Life, 2023 A pangenome is a collection of the common and unique genomes that are present in a given species. It combines the genetic information of all the genomes sampled, resulting in a large and diverse range of genetic material.
Paolo Abondio +2 more
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Structural Variations of Agriculture in the Pacific [PDF]
Agricultural Economics, 1987 AbstractAgricultural shares of output and employment in thirteen Pacific basin countries are analyzed with reference to a global baseline for 1980. Per‐capita output parity ratios are lower in the ASEAN, ANICs, and Japan as compared to their trading partners in North America and Oceania. Wide differences in land‐labor ratios influence the directions of
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Prediction of structural variation
Current Opinion in Structural BiologyProteins are dynamic molecules that transition between conformational states to perform their functions, and characterizing the protein ensemble is important for understanding biology and therapeutic applications. While recent breakthroughs in machine learning have enabled the prediction of high-quality static models of individual proteins, generating ...
Yogesh Kalakoti +2 more
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Somatic structural variation and cancer [PDF]
Briefings in Functional Genomics, 2015 With the advent of next-generation sequencing technologies, we have witnessed a rapid pace of discovery of new patterns of somatic structural variation in cancer genomes, and an attempt to figure out their underlying mechanisms. Some of these mechanisms are associated with particular cancer types, and in some cases are the main cause of the structural ...
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Balancing selection on genomic deletion polymorphisms in humans
eLife, 2023 A key question in biology is why genomic variation persists in a population for extended periods. Recent studies have identified examples of genomic deletions that have remained polymorphic in the human lineage for hundreds of millennia, ostensibly owing
Alber Aqil +3 more
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Viruses, 2019 The genetic diversity of orthohepadnaviruses is not yet fully understood. This study was conducted to investigate the role of structural variations (SVs) in their diversity. Genetic sequences of orthohepadnaviruses were retrieved from databases.
Kei Fujiwara +6 more
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Large-Scale Structural Variation Detection in Subterranean Clover Subtypes Using Optical Mapping
Frontiers in Plant Science, 2018 We selected two genetically diverse subspecies of the Trifolium model species, subterranean clover cvs. Daliak and Yarloop. The structural variations (SVs) discovered by Bionano optical mapping (BOM) were validated using Illumina short reads.
Yuxuan Yuan +13 more
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