Results 71 to 80 of about 1,047,704 (361)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Judging the Law of Politics [PDF]
, 2005 In this Review Essay I explore the rights-structure debate that has captivated the attention of election law scholars. The Essay juxtaposes the recent work of a leading individualist Professor Richard Hasen\u27s new book, The Supreme Court and Election ...
Charles, Guy-Uriel
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Studi Perbandingan Paradigma Fungsionalisme Structural VS Strukturalisme Levi-Strauss
Asketik, 2018 This study aims to compare two paradigms functional paradigm (structural) vs. structuralism Levi-Strauss. To answer questions about both these paradigms will use a comparative study between functionalism paradigm theory or functionalism (structural) and ...
Intan Sari Devi
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Twilight of Structuralism in Linguistics?
Forum Lingwistyczne, 2016 The Twilight of Structuralism in Linguistics? This article attempts to offer a brief description of the overall situation in contemporary linguistics in the context of the changes taking place.
Ewa Jędrzejko
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Podstawowe założenia strukturalizmu w filozofii matematyki
Zagadnienia Filozoficzne w Nauce, 2009 The notion of a structure is one of fundamental notions in mathematics: we speak of geometrical, topological, probabilistic, differential etc. structures.
Krzysztof Wójtowicz
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CONSUMPTION AS A SOCIAL STATUS SYMBOL IN STRUCTURALISM
Наука Красноярья, 2014 The article looks at the basic theoretical concepts of the political economy of the sign (structuralism, postmodernity) and their development in the theory of power based on the work by J. Baudrillard ‘For a Critique of the Political Economy of the Sign’.
N. D. Naydenov, T. A. Kirosova
doaj +1 more source