Results 21 to 30 of about 10,109,694 (374)

Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy. [PDF]

, 2014
Membrane ion channels regulate key cellular functions and their activity is dependent on their 3D structure. Atomic force microscopy (AFM) images 3D structure of membrane channels placed on a solid substrate.
Arce, Fernando Teran, Cohen, Daniel A, Lal, Ratnesh, Patel, Nirav R, Quist, Arjan P, Ramachandran, Srinivasan   +5 more
core   +2 more sources

The relationship between redox enzyme activity and electrochemical potential—cellular and mechanistic implications from protein film electrochemistry [PDF]

, 2011
In protein film electrochemistry a redox protein of interest is studied as an electroactive film adsorbed on an electrode surface. For redox enzymes this configuration allows quantification of the relationship between catalytic activity and ...
Ackrell, Anderson, Anderson, Andrew G. Mayes, Andrew J. Gates, Angove, Armstrong, Armstrong, Armstrong, Armstrong, Armstrong, Arnoux, Bamford, Bekker, Berks, Blumberger, Blumberger, Buc, Butler, Butler, Chun Yip To, Clarke, Costa, David J. Richardson, Davis, de Vries, Dementin, Dias, Dridge, Eddowes, Ellington, Elliott, Field, Flores, Fourmond, Fourmond, Fourmond, Frangioni, Frew, Gates, Gates, Gemma L. Kemp, Georgellis, Gwyer, Hagedoorn, Hanson, Healy, Heering, Hirst, Hofmann, Hunte, Immoos, Ivanov, James Mann, Jepson, Jepson, Jeuken, Julea N. Butt, Kell, Kemp, Lin, Léger, Léger, Léger, Marritt, Marsili, Moore, Murgida, Niki, Otten, Otten, Page, Pershad, Potter, Ramirez, Richardson, Ridnour, Sears, Sears, Simons, Sophie J. Marritt, Sun, Tenderholt, Tenderholt, Thauer, Tipmanee, Wang, Westerhoff, Yeh, Zuman   +89 more
core   +1 more source

Antibacterial Properties of Polyphenols: Characterization and QSAR (Quantitative Structure–Activity Relationship) Models

Frontiers in Microbiology, 2019
Besides their established antioxidant activity, many phenolic compounds may exhibit significant antibacterial activity. Here, the effect of a large dataset of 35 polyphenols on the growth of 6 foodborne pathogenic or food-spoiling bacterial strains ...
Lynda Bouarab-Chibane, V. Forquet, P. Lanteri, Y. Clément, Lucie Léonard-Akkari, N. Oulahal, P. Degraeve, C. Bordes   +7 more
semanticscholar   +1 more source

Structure-activity relationship in monosaccharide-based Toll-like receptor 4 (TLR4) antagonists [PDF]

, 2018
The structure-activity relationship was investigated in a series of synthetic TLR4 antagonists formed by a glucosamine core linked to two phosphate esters and two linear carbon chains.
Airoldi, Cristina, Beyaert, Rudi, Billod, Jean-Marc, Braun, Harald, Calabrese, Valentina, Ciaramelli, Carlotta, Facchini, Fabio A, Forcella, Matilde, Fusi, Paola, Jerala, Roman, Lapenta, Fabio, Martin-Santamaria, Sonsoles, Minotti, Alberto, Palmer, Charys, Peri, Francesco, Pirianov, Grisha, Rapisarda, Silvia, Schromm, Andra B, Zaffaroni, Lenny   +18 more
core   +3 more sources

Investigating the Structure–Activity Relationship of the Insecticidal Natural Product Rocaglamide

CHIMIA, 2017
The natural product Rocaglamide (1), isolated from the tree Aglaia elliptifolia, is a compelling but also challenging lead structure for crop protection.
Roger G. Hall, Ian Bruce, Nigel G. Cooke, Louis J. Diorazio, Fredrik Cederbaum, Markus R. Dobler, Ed Irving   +6 more
doaj   +1 more source

Electrochemical behavior of indolone-N-oxides: Relationship to structure and antiplasmodial activity [PDF]

, 2012
Indolone-N-oxides exert high parasiticidal activity at the nanomolar level in vitro against Plasmodiumfalciparum, the parasite responsible for malaria.
Fabre, Paul-Louis, Ibrahim, Hany, Montrose, Armelle, Nepveu, Françoise, Nguyen, Thi Hoang Yen, Perio, Pierre, Reybier, Karine   +6 more
core   +3 more sources

Synthesis and Fungicidal Activity of β-Carboline Alkaloids and Their Derivatives

Molecules, 2015
A series of β-Carboline derivatives were designed, synthesized, and evaluated for their fungicidal activities in this study. Several derivatives electively exhibited fungicidal activities against some fungi.
Zhibin Li, Shaohua Chen, Shaowen Zhu, Jianjun Luo, Yaomou Zhang, Qunfang Weng   +5 more
doaj   +1 more source

Biosynthesis, chemical structure, and structure-activity relationship of orfamide lipopeptides produced by Pseudomonas protegens and related species [PDF]

, 2016
Orfamide type cyclic lipopeptides (CLPs) are biosurfactants produced by Pseudomonas and involved in lysis of oomycete zoospores, biocontrol of Rhizoctonia and insecticidal activity against aphids.
Geudens, Niels, Höfte, Monica, Kieu Phuong, Nam, Ma, Zongwang, Martins, José, Ongena, Marc, Sinnaeve, Davy   +6 more
core   +3 more sources

Synthesis and Antibacterial Evaluation of N-phenylacetamide Derivatives Containing 4-Arylthiazole Moieties

Molecules, 2020
A series of new N-phenylacetamide derivatives containing 4-arylthiazole moieties was designed and synthesized by introducing the thiazole moiety into the amide scaffold.
Hui Lu, Xia Zhou, Lei Wang, Linhong Jin
doaj   +1 more source

Small molecule compounds with good anti-inflammatory activity reported in the literature from 01/2009 to 05/2021: a review

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Inflammation and disease are closely related. Inflammation can induce various diseases, and diseases can promote inflammatory response, and two possibly induces each other in a bidirectional loop.
Ming Bian, Qian-qian Ma, Yun Wu, Huan-huan Du, Gong Guo-hua   +4 more
doaj   +1 more source