The Relationship between the Structure and the Activity of Pyrethroids [PDF]
RESP ...
Elliott, M.
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Exploring the relationship between physical activity knowledge, health outcomes expectancies, and behavior [PDF]
Background: Despite clear health benefits of physical activity, previous research has been limited in linking knowledge of physical activity recommendations to actual behavior.
Bauman, Adrian +2 more
core
Structural insights and biological activities of flavonoids: Implications for novel applications
Flavonoids are a major class of polyphenolic compounds that occur naturally in plants and are widely distributed in various dietary products. Flavonoids exhibit prominent physicochemical properties and biological activities, thereby garnering ...
Sheng Tang +7 more
doaj +1 more source
Phomentrioloxin is a phytotoxic geranylcyclohexenetriol produced in liquid culture by Phomopsis sp. (teleomorph: Diaporthe gulyae), a potential mycoherbicide proposed for the control of the annual weed Carthamus lanatus.
Gavin Ash +14 more
core +1 more source
The Relationship between Physical Activity and Body Mass Index: Issues in Model Specification [PDF]
*Objective:* To investigate the best statistical models that describe the effect of physical activity on BMI. *Design:* Cross-sectional analyses of physical activity and BMI data.Subjects: 107 obese, overweight, and healthy college students ...
Gizachew Tiruneh, Gizachew Tiruneh
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Relationship Between Structure And Antimicrobial Activity Of Zinc Oxide Nanoparticles: An Overview
Bruna Lallo da Silva,1 Marina Paiva Abuçafy,1 Eloisa Berbel Manaia,1 João Augusto Oshiro Junior,1 Bruna Galdorfini Chiari-Andréo,1,2 Rosemeire CL R Pietro,1 Leila Aparecida Chiavacci1 1Department of Drugs and Medicines, School of ...
Lallo da Silva B +6 more
doaj
Insight into Janus kinases specificity: From molecular architecture to cancer therapeutics
Janus Kinases (JAKs) play a crucial role as therapeutic targets for various cancers. However, the current JAK inhibitors (JAKi) available have limited therapeutic benefits due to their lack of selectivity.
Tian‐Hua Wei +18 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source

