Results 71 to 80 of about 177,707 (371)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Search for a Solution of the Pioneer Anomaly [PDF]

, 2007
In 1972 and 1973 the Pioneer 10 and 11 missions were launched. They were the first to explore the outer solar system and achieved stunning breakthroughs in deep-space exploration. But beginning in about 1980 an unmodeled force of \sim 8 \times 10^{-8} cm/
Anderson J. D., Baum R., Danby J. M.A., Firmly R. O., Flandro G. A., Grosser M., Guman M. D., John D. Anderson, le Verrier U. J.J., Michael Martin Nieto, Nieto M. M., Olsen Ø., Sanders R. H., Wolverton M.   +13 more
core   +1 more source

Cardiac stunning during haemodialysis: the therapeutic effect of intra-dialytic exercise

Clinical Kidney Journal, 2019
Background Cardiovascular risk is elevated in end-stage renal disease. Left ventricular (LV) dysfunction is linked to repetitive transient ischaemia occurring during haemodialysis (HD).
S. McGuire, E. Horton, D. Renshaw, K. Chan, A. Jiménez, H. Maddock, N. Krishnan, G. McGregor   +7 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Why the Cameron-Clegg coalition will be a shock to both Tory and Liberal Democrat voters [PDF]

, 2010
There has been intensive speculation about how Conservative and Liberal Democrat voters will react to the coalition government cemented in their name.
Norris, Pippa
core  

Kneadings, Symbolic Dynamics and Painting Lorenz Chaos. A Tutorial

, 2012
A new computational technique based on the symbolic description utilizing kneading invariants is proposed and verified for explorations of dynamical and parametric chaos in a few exemplary systems with the Lorenz attractor.
Abad A., Afraimovich V., Afraimovich V., ANDREY SHILNIKOV, Barrio R., Barrio R., Bykov V. V., Glendinning P., Gonchenko S. V., Hubner U., LEONID SHILNIKOV, Malkin M., ROBERTO BARRIO, Roshchin N., Rychlic M., Shilnikov A., Shilnikov L., Shilnikov L., Shilnikov L., Shilnikov L. P.   +19 more
core   +1 more source

Welfare of horses at slaughter

EFSA Journal
The objective of this Scientific Opinion is to assess the hazards and welfare consequences associated with the slaughter of horses for human consumption.
EFSA Panel on Animal Health and Welfare (AHAW), Søren Saxmose Nielsen, Julio Alvarez, Anette Boklund, Sabine Dippel, Fernanda Dorea, Jordi Figuerola, Mette Herskin, Miguel Angel Miranda Chueca, Eleonora Nannoni, Romolo Nonno, Anja Riber, Karl Stahl, Jan Arend Stegeman, Hans‐Hermann Thulke, Frank Tuyttens, Christoph Winckler, Mohan Raj, Antonio Velarde, Denise Candiani, Yves Van der Stede, Virginie Michel   +21 more
doaj   +1 more source

Scientific Opinion on monitoring procedures at slaughterhouses for poultry

EFSA Journal, 2013
This scientific opinion proposes toolboxes of welfare indicators, and their corresponding outcomes of consciousness, unconsciousness or death, for developing monitoring procedures at slaughterhouses for poultry stunned using electrical waterbaths and gas
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Harvest Method Influences Color Stability of Longissimus Lumborum Steaks from Bos indicus Cattle

Meat and Muscle Biology, 2019
Brazil is a major beef exporter to countries where religious slaughter without stunning is mandatory. Fresh beef color influences consumers’ purchase decisions, and harvest method influences beef quality attributes, such as color, water holding capacity,
Ana Paula A. A. Salim, Anna C. V. C. S. Canto, Carlos A. Conte-Junior, Fernanda M. Viana, Maria Lucia G. Monteiro, Pedro H. N. Panzenhagen, Surendranath P. Suman   +6 more
doaj   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source