Results 61 to 70 of about 28,805 (298)

Welfare of horses at slaughter

EFSA Journal
The objective of this Scientific Opinion is to assess the hazards and welfare consequences associated with the slaughter of horses for human consumption.
EFSA Panel on Animal Health and Welfare (AHAW), Søren Saxmose Nielsen, Julio Alvarez, Anette Boklund, Sabine Dippel, Fernanda Dorea, Jordi Figuerola, Mette Herskin, Miguel Angel Miranda Chueca, Eleonora Nannoni, Romolo Nonno, Anja Riber, Karl Stahl, Jan Arend Stegeman, Hans‐Hermann Thulke, Frank Tuyttens, Christoph Winckler, Mohan Raj, Antonio Velarde, Denise Candiani, Yves Van der Stede, Virginie Michel   +21 more
doaj   +1 more source

Molecular and Cellular Mechanisms of Myocardial Stunning

, 1999
The past two decades have witnessed an explosive growth of knowledge regarding postischemic myocardial dysfunction or myocardial “stunning.” The purpose of this review is to summarize current information regarding the pathophysiology and pathogenesis of ...
Roberto Bolli, Eduardo Marbán
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Is ongoing ritual slaughter of livestock justifiable in modern America?

Journal of Applied Animal Research, 2021
All livestock animals raised for food in America must be rendered immediately unconscious prior to slaughter to prevent needless suffering. An exception to this legal requirement exists for ritually-slaughtered animals.
Sean Leffert
doaj   +1 more source

Translational studies to understand myocardial stunning in acute myocardial infarction [PDF]

Myocardial stunning is a reversible contractile dysfunction that persists despite the resolution of myocardial ischemia. It is commonly associated with acute myocardial infarction. However, myocardial stunning also occurs in other acute cardiomyopathies,
Espinosa Shekka, Aaron
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Effects of stunning methods on pre rigor changes in rainbow trout (Oncorhynchus mykiss) reared at two different temperatures

Italian Journal of Animal Science, 2020
The effects of two stunning methods (carbon monoxide asphyxia, CO, and electroshock, E) on blood plasma parameters, rigor index, fillet pH and shape changes, ATP breakdown and Adenylate Energy Charge (AEC) in muscle immediately post mortem were ...
Anna Concollato, Giulia Secci, Antonella Dalle Zotte, Sheyla Cristina Vargas, Rolf Erik Olsen, Adja Cristina Lira de Medeiros, Giuliana Parisi   +6 more
doaj   +1 more source

Scientific Opinion on the use of carbon dioxide for stunning rabbits [PDF]

EFSA Journal, 2013
The Panel on Animal Health and Welfare was asked to deliver a scientific opinion on the use of carbon dioxide for stunning rabbits. Specifically, EFSA was asked to give its view on the findings of the study performed by the Polytechnic University of ...
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Electrical stunning of poultry

, 2018
This chapter provides a summary of the latest electrical stunning methods for poultry in relation to EU and OIE legislature concerning animal welfare at killing.
Hindle, Vincent, Vincent Hindle, Lambooij, Bert, Bert Lambooij   +3 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source