Results 81 to 90 of about 16,203 (230)
Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins
Nature CommunicationsDinoflagellates and cyanobacteria produce saxitoxin (STX) and ~50 congeners that disrupt bioelectrical signals by blocking voltage-gated sodium channels (NaVs). Consuming seafood carrying these toxins causes paralytic shellfish poisoning (PSP).
Sandra Zakrzewska +13 more
doaj +1 more source
Detection of stx and stx genes in Pennsylvanian white-tailed deer.
Toxins, 2013 Shiga toxin-producing E. coli carrying the stx(1) and/or stx(2) genes can cause multi-symptomatic illness in humans. A variety of terrestrial and aquatic environmental reservoirs of stx have been described. Culture based detection of microbes in deer species have found a low percentage of samples that have tested positive for Stx-producing microbes ...
Whitney M, Kistler +2 more
openaire +1 more source
Journal of Phycology, Volume 62, Issue 3, Page 801-817, June 2026.Abstract Cyanobacteria are cosmopolitan, important components of biomass with a remarkable ability to synthesize a diverse array of bioactive compounds, some of which may have toxic effects on other organisms and ecosystems. In this study, filamentous cyanobacterial strains isolated predominantly from temperate European freshwaters (Aphanizomenon ...
Łukasz Wejnerowski +14 more
wiley +1 more source
Bacteriophages as Pathogens and Immune Modulators?
mBio, 2013 While Shiga toxins (Stx) are key determinants of enterohemorrhagic Escherichia coli (EHEC) pathophysiology in humans, their dissemination to target organs following gastrointestinal EHEC infection is still poorly understood.
A. Lengeling, A. Mahajan, D. L. Gally
doaj +1 more source
PLoS ONE, 2021 Shiga toxin-producing Escherichia coli (STEC) have been linked to food-borne disease outbreaks. As PCR is routinely used to screen foods for STEC, it is important that factors leading to inconsistent detection of STEC by PCR are understood.
Vinicius Silva Castro +7 more
doaj +1 more source
Advanced Functional Materials, Volume 36, Issue 38, 11 May 2026.ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based local
Fatima Hameedat +11 more
wiley +1 more source
, 2012 aNumbers of isolates with the corresponding Stx-associated bacteriophage sequences in the insertion site. Numbers in parentheses indicate the isolate also positive for the expected stx.
Carrie Schmidt (112902) +5 more
core +1 more source
Sex steroids do not affect shigatoxin cytotoxicity on human renal tubular or glomerular cells
BMC Nephrology, 2002 Background The greater susceptibility of children to renal injury in post-diarrheal hemolytic-uremic syndrome (HUS) may be related, at least in part, to heightened renal cell sensitivity to the cytotoxic effect of Shiga toxin (Stx), the putative mediator
Kohan Donald E +2 more
doaj +1 more source
Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.Abstract The 2025 Leon Thal Summit convened an international panel of clinicians, neuroscientists, neuropathologists, and neuroimaging specialists to evaluate the current state of biomarker development for chronic traumatic encephalopathy (CTE) and to outline priorities for advancing translational research for this important area.
Charles Bernick +24 more
wiley +1 more source
STX increases glucose-induced plasma insulin levels.
, 2013 A, Plasma insulin concentration (µg/l) measured at 30 min after a 2 g/kg glucose load in male mice treated with vehicle or 100 µg/kg STX; n≥7 mice/condition.
Sergi Soriano (184947) +6 more
core +1 more source