Results 61 to 70 of about 16,203 (230)

Dynamic changes in Shiga toxin (Stx) 1 transducing phage throughout the evolution of O26:H11 Stx-producing Escherichia coli

open access: yes, 2023
Shiga toxin (Stx) is the key virulence factor of Stx-producing Escherichia coli (STEC). All known Stxs (Stx1 and Stx2) are encoded by bacteriophages (Stx phages).
Yasuhiro Gotoh   +4 more
core   +1 more source

A Rapid and Sensitive Method to Measure the Functional Activity of Shiga Toxins in Human Serum

open access: yesToxins, 2015
Shiga toxins (Stx) have a definite role in the development of hemolytic uremic syndrome in children with hemorrhagic colitis caused by pathogenic Stx-producing Escherichia coli (STEC) strains. The dramatic effects of these toxins on the microvasculature
Valentina Arfilli   +5 more
doaj   +1 more source

High diversity in the regulatory region of Shiga toxin encoding bacteriophages

open access: yesBMC Genomics, 2022
Background Enterohemorrhagic Escherichia coli (EHEC) is an emerging health challenge worldwide and outbreaks caused by this pathogen poses a serious public health concern.
Annette Fagerlund   +3 more
doaj   +1 more source

Association of recurrence patterns and outcome with HR and HER2 status in patients with resected brain metastases from breast cancer

open access: yesInternational Journal of Cancer, Volume 159, Issue 2, Page 440-449, 15 July 2026.
What's new? While treatment strategies for solid brain metastases have been relatively uniform across cancer subtypes, tailored approaches are warranted. In this observational study, intracranial recurrences after microsurgical resection occurred significantly earlier and more frequently at distant sites in patients with triple‐negative breast cancer ...
Jonathan Weller   +14 more
wiley   +1 more source

Uncovering the Complex Transcriptome Response of Mytilus chilensis against Saxitoxin: Implications of Harmful Algal Blooms on Mussel Populations. [PDF]

open access: yesPLoS ONE, 2016
Saxitoxin (STX), a principal phycotoxin contributing to paralytic shellfish poisoning, is largely produced by marine microalgae of the genus Alexandrium. This toxin affects a wide range of species, inducing massive deaths in fish and other marine species.
Camille Detree   +3 more
doaj   +1 more source

Latent density discrepancies in commercial lung‐equivalent inserts and their clinical dosimetric impact

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 7, July 2026.
Abstract Background Accurate heterogeneity correction in high‐precision radiotherapy relies on precise computed tomography (CT) number‐to‐density conversion via the Hounsfield unit look‐up table (HLUT). While physical properties of tissue‐equivalent materials are generally assumed consistent with manufacturer specifications, an independent audit ...
Minoru Nakao   +5 more
wiley   +1 more source

Effects ofSaxitoxin (STX) and Veratridine on BacterialNa + -K + Fluxes: a Prokaryote-BasedSTXBioassay [PDF]

open access: yesApplied and Environmental Microbiology, 2003
ABSTRACT Saxitoxin (STX) is a potent natural sodium channel blocker and represents a significant health concern worldwide. We describe here the antagonistic effects of STX and veratridine (VTD), an Na + channel activator, on three gram-negative bacteria and their application to an STX bioassay. STX reduced
F. Pomati   +3 more
openaire   +3 more sources

Biosensors for Biotoxins Detection and Monitoring

open access: yesAdvanced Sensor Research, Volume 5, Issue 6, June 2026.
This review examines state‐of‐the‐art biosensing platforms for biotoxin detection, including antibody‐, aptamer‐, CRISPR‐, nanopore‐, whole cells‐ and MIP‐based sensors. It highlights advances in ultra‐sensitive detection, real‐matrix validation in food and water, and multiplexed analysis, and discusses how the integration with machine learning ...
Alissa Agerova   +2 more
wiley   +1 more source

Neutralizing activity of anti-Stx IgY.

open access: yes, 2013
(A) hpStx-1, (B) hpStx-2 and (C) hpStx-2A1B were mixed with serial dilutions of anti-Stx-1 IgY and anti-Stx-2 IgY, and incubated for 1 h at 37°C. The mixture was subjected to the cytotoxicity assay.
Paola Neri (341635)   +9 more
core   +1 more source

Structure of the saxiphilin:saxitoxin (STX) complex reveals a convergent molecular recognition strategy for paralytic toxins [PDF]

open access: yes, 2019
Dinoflagelates and cyanobacteria produce saxitoxin (STX), a lethal bis-guanidinium neurotoxin causing paralytic shellfish poisoning. A number of metazoans have soluble STX-binding proteins that may prevent STX intoxication.
Du Bois, J   +6 more
core   +1 more source

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