Results 41 to 50 of about 16,250 (229)

The novel estrogen receptor modulator STX attenuates Amyloid-β neurotoxicity in the 5XFAD mouse model of Alzheimer's disease

open access: yesNeurobiology of Disease, 2022
Based on previous evidence that the non-steroidal estrogen receptor modulator STX mitigates the effects of neurotoxic Amyloid-β (Aβ) in vitro, we have evaluated its neuroprotective benefits in a mouse model of Alzheimer's disease.
Joseph F. Quinn   +8 more
doaj   +1 more source

Shiga toxin-producing Escherichia coli in yaks (Bos grunniens) from the Qinghai-Tibetan Plateau, China. [PDF]

open access: yesPLoS ONE, 2013
Shiga toxin (Stx)-producing Escherichia coli (STEC) are recognized as important human pathogens of public health concern. Many animals are the sources of STEC.
Xiangning Bai   +11 more
doaj   +1 more source

Neutralizing activity of anti-Stx IgY. [PDF]

open access: yes, 2013
(A) hpStx-1, (B) hpStx-2 and (C) hpStx-2A1B were mixed with serial dilutions of anti-Stx-1 IgY and anti-Stx-2 IgY, and incubated for 1 h at 37°C. The mixture was subjected to the cytotoxicity assay.
Paola Neri (341635)   +9 more
core   +1 more source

Primary Human Colon Epithelial Cells (pHCoEpiCs) Do Express the Shiga Toxin (Stx) Receptor Glycosphingolipids Gb3Cer and Gb4Cer and Are Largely Refractory but Not Resistant towards Stx [PDF]

open access: yes, 2021
Shiga toxin (Stx) is released by enterohemorrhagic Escherichia coli (EHEC) into the human intestinal lumen and transferred across the colon epithelium to the circulation.
Johanna Detzner   +6 more
core   +1 more source

In Vivo Transduction of an Stx-Encoding Phage in Ruminants [PDF]

open access: yesApplied and Environmental Microbiology, 2006
ABSTRACTWe assessed the ability of a kanamycin-marked Stx phage to move into a commensal, ovineEscherichia colistrain in the ruminant gastrointestinal tract. Transduction was detected in 19/24 sheep tested, resulting in the recovery of 47 transductants.
Cornick, Nancy   +4 more
openaire   +4 more sources

Effect of anti-Stx IgY given via different routes from Stx on mortality of mice. [PDF]

open access: yes, 2013
(A) ppStx-1 (2.5 times LD50) and (B) ppStx-2 (2 times LD50) were administered i.p. to ddY mice. Anti-Stx-1 IgY and anti-Stx-2 IgY were given i.v. at doses of 50 and 100 mg/kg at 10 min before challenge. Control mice were given PBS instead of anti-Stx IgY.
Paola Neri (341635)   +9 more
core   +1 more source

Shiga Toxin‒Producing Escherichia coli Diagnoses from Health Practitioners, Queensland, Australia

open access: yesEmerging Infectious Diseases
In Queensland, Australia, 31 of 96 Shiga toxin‒producing Escherichia coli cases during 2020–2022 were reported by a specialty pathology laboratory servicing alternative health practitioners.
Ashish C. Shrestha   +6 more
doaj   +1 more source

Serum VNA-Stx levels following Ad/VNA-Stx administration via different routes. [PDF]

open access: yes, 2014
aRoutes by which Ad was administered; iv-intravenous, ip-intraperitoneal, im-intramuscular, sq-subcutaneous.bSerum was collected 4 days post-treatment and VNA levels estimated by dilution ELISA for binding to toxin targets.Serum VNA-Stx levels following ...
Igor Dmitriev (623384)   +7 more
core   +1 more source

Marine toxins - saxitoxin (STX) and tetrodotoxin (TTX) [PDF]

open access: yes, 2015
Saxitoxin (STX) and tetrodotoxin (TTX) are two of the most poisonous marine biotoxins known. They have a very interesting history, both used as a means for suicide and murder STX has been announced publicly by the world`s governments as a chemical weapon,
Georgieva, Marieta   +1 more
core   +1 more source

Occurrence of Multiple stx1 Genes and Rare Genomic Variation in stx1 Shiga Toxin-Producing Escherichia coli

open access: yesMicroorganisms
Shiga toxin-producing Escherichia coli are important foodborne pathogens. There are several subtypes of the Shiga toxin Stx known, with Stx2 (a–o) being more diverse than Stx1 (a, c, d).
Michaela Projahn   +6 more
doaj   +1 more source

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