Results 31 to 40 of about 17,611 (220)

Insights into the genome architecture and evolution of Shiga toxin encoding bacteriophages of Escherichia coli

open access: yesBMC Genomics, 2021
Background A total of 179 Shiga toxin-producing Escherichia coli (STEC) complete genomes were analyzed in terms of serotypes, prophage coding regions, and stx gene variants and their distribution.
Graça Pinto   +5 more
doaj   +1 more source

Shiga Toxin Is Transported into the Nucleoli of Intestinal Epithelial Cells via a Carrier-Dependent Process

open access: yesToxins, 2010
Shiga toxin (Stx) produced by the invasive Shigella dysenteriae serotype 1 (S. dysenteriae1) causes gastrointestinal and kidney complications. It has been assumed that Stx is released intracellularly after enterocyte invasion by S. dysenteriae1. However,
Boris Baibakov   +4 more
doaj   +1 more source

Intervention with Shiga Toxin (Stx) Antibody after Infection by Stx‐ProducingEscherichia coli [PDF]

open access: yesThe Journal of Infectious Diseases, 2001
Shiga toxins (Stxs) produced by Escherichia coli (STEC) cause systemic vascular damage, manifested as hemolytic uremic syndrome in humans and as edema disease in pigs. Edema disease, a naturally occurring disease of pigs, was used to determine whether Stx antibodies, administered after infection and after the onset of Stx production, could prevent the ...
Matise, Ilze   +5 more
openaire   +3 more sources

The Probiotic Escherichia coli Strain Nissle 1917 Combats Lambdoid Bacteriophages stx and λ

open access: yesFrontiers in Microbiology, 2018
Shiga toxin (Stx) producing E. coli (STEC) such as Enterohemorrhagic E. coli (EHEC) are the major cause of foodborne illness in humans. In vitro studies showed the probiotic Escherichia coli strain Nissle 1917 (EcN) to efficiently inhibit the production ...
Susanne Bury   +5 more
doaj   +1 more source

Cheating, facilitation and cooperation regulate the effectiveness of phage‐encoded exotoxins as antipredator molecules

open access: yesMicrobiologyOpen, 2019
Temperate phage encoded Shiga toxin (Stx) kills the bacterivorous predator, Tetrahymena thermophila, providing Stx+ Escherichia coli with a survival advantage over Stx− cells. Although bacterial death accompanies Stx release, since bacteria grow clonally
Iqbal Aijaz, Gerald B. Koudelka
doaj   +1 more source

Shiga Toxin Interaction with Human Intestinal Epithelium

open access: yesToxins, 2011
After ingestion via contaminated food or water, enterohaemorrhagic E. coli colonises the intestinal mucosa and produces Shiga toxins (Stx). No Stx-specific secretion system has been described so far, and it is assumed that Stx are released into the gut ...
Stephanie Schüller
doaj   +1 more source

The novel estrogen receptor modulator STX attenuates Amyloid-β neurotoxicity in the 5XFAD mouse model of Alzheimer's disease

open access: yesNeurobiology of Disease, 2022
Based on previous evidence that the non-steroidal estrogen receptor modulator STX mitigates the effects of neurotoxic Amyloid-β (Aβ) in vitro, we have evaluated its neuroprotective benefits in a mouse model of Alzheimer's disease.
Joseph F. Quinn   +8 more
doaj   +1 more source

SelExNet: A Self-Supervised Physics-Informed Framework for Multi-Channel Joint RF and Gradient Waveform Optimization in 2D Spatially Selective Excitation. [PDF]

open access: yesMagn Reson Med
ABSTRACT Purpose To introduce SelExNet: a self‐supervised framework for two‐dimensional spatially selective excitation that jointly optimizes radiofrequency (RF) pulses and gradient waveforms, and extends to multi‐channel transmission MRI. Methods Building on prior RF‐only and joint RF‐gradient optimization approaches, SelExNet couples neural RF and ...
Xiao Y   +5 more
europepmc   +2 more sources

In VivoAutopolysialylation and Localization of the Polysialyltransferases PST and STX [PDF]

open access: yesJournal of Biological Chemistry, 1998
A select group of mammalian proteins have been shown to possess alpha2,8-polysialylated oligosaccharide chains. The best studied of these proteins is the neural cell adhesion molecule (NCAM). Polysialylation of NCAM has been shown to decrease NCAM-dependent and independent cell adhesion.
B E, Close, K J, Colley
openaire   +2 more sources

Shiga toxin-producing Escherichia coli in yaks (Bos grunniens) from the Qinghai-Tibetan Plateau, China. [PDF]

open access: yesPLoS ONE, 2013
Shiga toxin (Stx)-producing Escherichia coli (STEC) are recognized as important human pathogens of public health concern. Many animals are the sources of STEC.
Xiangning Bai   +11 more
doaj   +1 more source

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