Results 71 to 80 of about 9,721 (212)
Frontiers in Molecular Neuroscience, 2015 Shiga toxin-producing Escherichia coli (STEC) can cause central nervous system (CNS) damage resulting in paralysis, seizures, and coma. The key STEC virulence factors associated with systemic illness resulting in CNS impairment are Shiga toxins (Stx ...
Fumiko eObata +6 more
doaj +1 more source
Investigation on the Evolution of Shiga Toxin-Converting Phages Based on Whole Genome Sequencing
Frontiers in Microbiology, 2020 Bacteriophages are pivotal elements in the dissemination of virulence genes. The main virulence determinants of Shiga Toxin producing E. coli, Shiga Toxins (Stx), are encoded by genes localized in the genome of lambdoid bacteriophages.
Michele Zuppi +7 more
doaj +1 more source
Advanced Materials, Volume 38, Issue 53, 21 September 2026.A soap‐film inspired strategy enables the fabrication of ultrathin yet robust GelMA‐PAAm membranes for breathing lung culture. The hydrogel membrane supports long‐term cyclic deformation under air‐liquid interface conditions, enabling physiologically relevant breathing motions of engineered lung tissue culture. ABSTRACT Breathing continuously stretches
Yunji Lee +9 more
wiley +1 more source
Nach §34 IfSG müssen in Deutschland Personen, die Enterohämorrhagische Escherichia coli (EHEC) ausscheiden, bis zum Ausschluss einer relevanten Infektionsgefahr von Gemeinschaftseinrichtungen ferngehalten werden. Die Wiederzulassung orientiert sich an Empfehlungen des Robert Koch-Instituts (EHEC: Überarbeitung der RKI-Empfehlungen für die ...
Emanuel Heitlinger +4 more
openaire +1 more source
, 2002 Hemolytic-uremic syndrome (HUS) is a serious complication predominantly associated with infection by enterohemorrhagic Escherichia coli (EHEC), such as E. coli O157:H7. EHEC can produce Shiga toxin 1 (Stx1)
Kerry Chios +7 more
core +1 more source
BMC Immunology, 2010 Backgound Shiga toxin 2 (Stx2), one of two Stx liberated by Stx-producing Escherichia coli, is composed of an A subunit monomer and a B subunit pentamer, and is directly linked with hemolytic uremic syndrome in children. The pentameric B subunit binds to
Tzipori Saul +5 more
doaj +1 more source
Antibody recognition of Shiga toxins (Stxs): computational identification of the epitopes of Stx2 subunit A to the antibodies 11E10 and S2C4. [PDF]
PLoS ONE, 2014 We have recently developed a new method to predict the epitopes of the antigens that are recognized by a specific antibody. In this work, we applied the method to identify the epitopes of the Shiga toxin (Stx2 subunit A) that were bound by two specific ...
Yongjun Jiao +4 more
doaj +1 more source
Syntaxin‐3 Regulates Tight Junction Assembly in Human Retinal Pigment Epithelium
Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.ABSTRACT The retinal pigment epithelium (RPE) consists of polarized epithelial cells, serving as a support system for photoreceptor maintenance, where the polarity is contributed by the distribution of syntaxins (STX) within the cell. STX3, a known regulator of apical trafficking in epithelial cells, was previously understood to be absent in human RPE ...
Athira Ramesh +3 more
wiley +1 more source
Binding of Stx1 and Stx2 to purified glycolipids and mixtures.
, 2013 Stx binding was assessed by ELISA at 10 nM for both Stx1 (white columns) and Stx2 (black columns) at 4°C. The RFU signal is the mean of three independent experiments and error bars indicate SD. Since different antibodies were used to detect Stx1 and Stx2,
Karen M. Gallegos (333260) +5 more
core +1 more source
Natural Product‐Derived Vesicles in Nanotherapeutics
Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley +1 more source