Frontiers in Pharmacology, 2014 Flabellaria paniculata Cav. (Malpighiaceae) is a climbing shrub, the preparations of which are used in the treatment of wounds and ulcers in Nigeria and Ghana. This study investigated the sub-chronic toxicity profile of the hydroethanolic leaf extract of
Abidemi James Akindele +4 more
doaj +1 more source
Clinical Phytoscience, 2022 Background Ulcer remains a health challenge worldwide with antibiotics and proton pump inhibitors as major management therapy. The study investigated the acute, sub-chronic toxicity and gastrointestinal protective activity of a polyherbal formulation ...
Funmileyi Olubajo Awobajo +3 more
doaj +1 more source
Multiple Targets of Toxicity in Environmental Exposure to Low-Dose Cadmium
Toxics, 2022 Dietary assessment reports and population surveillance programs show that chronic exposure to low levels of environmental cadmium (Cd) is inevitable for most people, and adversely impacts the health of children and adults.
Soisungwan Satarug +2 more
doaj +1 more source
28-Day Oral Chronic Toxicity Study of Arctigenin in Rats
Frontiers in Pharmacology, 2018 Arctium lappa (burdock) is the most popular daily edible vegetable in China and Japan because of its general health tonic effects. Previous studies focused on the beneficial role of Arctigenin but neglected its potential side-effects and toxicities.
Yu-jun Tan +33 more
doaj +1 more source
Studi Mengenai Toksisitas Surfaktan Deterjen, Alkyl Sulfate (as), Terhadap Post Larva Udang Windu Penaeus Monodon Fabr [PDF]
, 2008 Penelitian ini dilakukan untuk mengetahui toksisitas surfaktan deterjen alkyl sulfate (AS) terhadap post larva udang windu Penaeus monodon Fabr. Pada uji akut, udang windu PL10 dipaparkan pada media yang mengandung AS selama 96 jam dan dihitung nilai ...
Berlianti, B. (Berlianti) +2 more
core
Optimized Treatment Schedules for Chronic Myeloid Leukemia
, 2016 Over the past decade, several targeted therapies (e.g. imatinib, dasatinib, nilotinib) have been developed to treat Chronic Myeloid Leukemia (CML). Despite an initial response to therapy, drug resistance remains a problem for some CML patients.
Dingli, David +4 more
core +3 more sources
Chronic Kidney Disease of Unknown aetiology (CKDu) and multiple-ion interactions in drinking water
, 2017 Recent experimental work on the nephrotoxicity of contaminants in drinking water using laboratory mice, motivated by the need to understand the origin of chronic kidney disease of unknown aetiology is examined within our understanding of the hydration of
Dharma-wardana, M. W. C.
core +1 more source
Therapy of pancreatic cancer via an EphA2 receptor-targeted delivery of gemcitabine. [PDF]
, 2016 First line treatment for pancreatic cancer consists of surgical resection, if possible, and a subsequent course of chemotherapy using the nucleoside analogue gemcitabine.
Barile, Elisa +11 more
core +2 more sources
Evaluation of Albizia lebbeck and Curcuma longa Extracts on Gastrointestinal Motility, Safety, and Hematological Parameters: A Sub-Chronic Toxicity and Pharmacological Study [PDF]
Asia Pacific Journal of Medical ToxicologyBackground: Gastrointestinal disorders are prevalent worldwide, necessitating effective and safe therapeutic options. The use of herbal medicine dates back thousands of years, with various cultures employing plants to treat ailments.
Bushirat Fagbohun +7 more
doaj +1 more source
Acute and sub-chronic toxicological evaluation of hydro-methanolic extract of Coriandrum sativum L. seeds [PDF]
, 2012 Coriandrum sativum L. (CS) seeds are known to possess therapeutic potentials against a variety of physiological disorders. This study assesses acute and sub-chronic toxicity profile of hydro-methanolic extract of CS seeds using OECD guidelines.
Desai, Swati +3 more
core