Results 91 to 100 of about 3,864,827 (278)
Sub Chronic Toxicity Study of Coumacines
Pharmacognosy Journal, 2023 Wejdan Al-Shakarchi +3 more
openaire +1 more source
Advanced Functional Materials, EarlyView.A bio‐inspired biopolymeric implantable drug delivery platform enables localized and sustained release of 7‐ethyl‐10‐hydroxycamptothecin (SN‐38) in solid tumor treatment. The three‐dimensional (3D) structured crosslinked‐chitosan implants are fabricated via 3D‐printed molds and provide drug release over 3 months, significantly inhibiting tumor growth ...
Mercedes Lozano‐Garcia +12 more
wiley +1 more source
Mitochondrial toxicity of drugs [PDF]
, 2008 The introduction of this thesis concentrates on the cellular energy supplier and an important instrument in mediating cell death, mitochondrion. First, an overview is given to explain the biochemical properties of this organelle.
Waldhauser, Katri Maria
core +1 more source
Thermoresponsive Soft and Self‐Anchoring Cuff Electrode for Chronic Peripheral Interfaces
Advanced Functional Materials, EarlyView.A novel thermoresponsive, soft and self‐anchoring (TSSA) cuff electrode utilizing shape memory polymers achieves autonomous, sutureless peripheral nerve fixation. Driven by thermally induced pre‐strain and tissue adhesion, the device self‐closes and softens at body temperature, successfully minimizing mechanical mismatch. This adaptive platform ensures
Seungjun Lee +4 more
wiley +1 more source
Safety assessment of hydroethanolic rambutan rind extract: Acute and sub-chronic toxicity studies
, 2014 989-995This study evaluated the safety of rambutan rind extract (RRE) in male Wistar rats. While acute toxicity was evaluated by feeding the rats with single doses of RRE (1000, 2000, 3000, 4000, and 5000 mg/kg) and its sub-chronic toxicity was ...
Thinkratok, Aree +2 more
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Advanced Healthcare Materials, EarlyView.This study explores how the brain responds to implants of different properties. Hydrogels with various mechanical properties and pore sizes were implanted in adult rat brains. It is observed that hydrogels with mechanical property closely matched to the brain and 40 µm pore size elicit a pro‐healing response from the brain by modulating the immune ...
Ian Dryg +8 more
wiley +1 more source
Acute and sub-chronic oral toxicity study of black tea in rodents
Indian Journal of Pharmacology, 2015 Systematic oral toxicity study for black tea (Camellia sinensis), the most commonly consumed variety of tea, is lacking. The present study was undertaken to assess the iron load on black tea (Camellia sinensis) and its safety aspects in animals.The analysis of iron was done in six tea samples as per American Public Health Association method using flame
Sur, Tapas Kumar +4 more
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave +8 more
wiley +1 more source
Sub-chronic toxicological assessment of saxitoxin
, 2020 Risk = the probability that an adverse effect will be induced in an individual through contact with a particular substance Risk is a function of the amount ingested and toxicity 2 aspects to risk: Acute toxicity (one-off dose) used to set ARfD ARfD ...
Sarah Finch (15395276)
core
How is Nanoarchitectonics Shaping Extracellular Vesicle Research?
Advanced Healthcare Materials, EarlyView.The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake +5 more
wiley +1 more source