Results 91 to 100 of about 5,419,445 (302)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Predicting circRNA subcellular localization by fusing circRNA sequence and network information

Scientific Reports
CircRNAs have attracted more and more attentions in recent years as they play important roles in many biological processes. It is essential for determining the functions of circRNAs.
Lei Chen, Jinghai Hu, Bo Zhou
doaj   +1 more source

SNX16 negatively regulates the migration and tumorigenesis of MCF-7 cells

Cell Regeneration, 2013
Background: Sorting nexins are a large family of proteins that are associated with various components of the endosome system and they play many roles in processes such as endocytosis, intracellular protein trafficking and cell signaling.
Leilei Zhang, Dajiang Qin, Chunfang Hao, Xiaodong Shu, Duanqing Pei   +4 more
doaj   +1 more source

BlueBrain/BlueNaaS-Subcellular: 1.0.1

, 2022
A web environment for the simulation of brain molecular ...
Pavlo Getta, g-bar
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Influence of energy deficiency on the subcellular processes of Substantia Nigra Pars Compacta cell for understanding Parkinsonian neurodegeneration. [PDF]

Sci Rep, 2021
Muddapu VR, Chakravarthy VS.
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

TESTLoc: protein subcellular localization prediction from EST data

BMC Bioinformatics, 2010
Background The eukaryotic cell has an intricate architecture with compartments and substructures dedicated to particular biological processes. Knowing the subcellular location of proteins not only indicates how bio-processes are organized in different ...
Burger Gertraud, Shen Yao-Qing
doaj   +1 more source

Acknowledgement to Reviewers of Processes in 2016

, 2017
The editors of Processes would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2016.[...
Processes Editorial Office
core   +1 more source

Subcellular localization of Trypanosoma cruzi arginine kinase [PDF]

, 2009
Phosphoarginine is a cell energy buffer molecule synthesized by the enzyme arginine kinase. In Trypanosoma cruzi, the aetiological agent of Chagas’ disease, 2 different isoforms were identified by data mining, but only 1 was expressed during the parasite
Pereira, Claudio Alejandro, Canepa, Gaspar Exequiel, Miranda, Mariana Reneé, Bouvier, León Alberto   +3 more
core   +1 more source