Results 81 to 90 of about 5,419,445 (302)

Editorial: Subcellular computations and information processing

Frontiers in Synaptic Neuroscience, 2023
Tomoe Ishikawa, Tomoe Ishikawa, Ayako Wendy Ishikawa, Athanasia Papoutsi, Asami Tanimura, Keisuke Yonehara, Keisuke Yonehara, Keisuke Yonehara   +7 more
openaire   +3 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Subcellular Localization Prediction of Eukaryotic Protein

, 2009
[[abstract]]Biologically, the function of a protein is highly related to its subcellular localization. Accordingly, it is necessary to develop an automatic yet reliable method for protein subcellular localization prediction, especially when large-scale ...
Chen Shih Hao
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

PMLocMSCAM: Predicting miRNA Subcellular Localisations by miRNA Similarities and Cross‐Attention Mechanism

IET Systems Biology
Many studies have shown that microRNAs (miRNAs) play key roles in some important processes and human complicated diseases. In addition, they also have specific physiological roles at different cellular sites.
Jipu Jiang, Cheng Yan
doaj   +1 more source

RNA-binding protein interacting with circular RNAs: potential multitarget therapeutic strategies in ischaemic stroke

Stroke and Vascular Neurology
Numerous single neuroprotective agents have shown promising results in animal studies, but most have fallen short of expectations in large-scale clinical trials and reliable multitarget neuroprotective agents are still lacking in ischaemic stroke ...
Anding Xu, Dan Lu, Yanfang Liu
doaj   +1 more source

First person – Michael Robichaux

Disease Models & Mechanisms, 2022
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping early-career researchers promote themselves alongside their papers.
doaj   +1 more source

Regulation of mammalian microRNA processing and function by cellular signaling and subcellular localization [PDF]

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2008
For many microRNAs, in many normal tissues and in cancer cells, the cellular levels of mature microRNAs are not simply determined by transcription of microRNA genes. This mini-review will discuss how microRNA biogenesis and function can be regulated by various nuclear and cytoplasmic processing events, including emerging evidence that microRNA pathway ...
openaire   +2 more sources

Sequence analysis and subcellular localization of crucian carp Carassius auratus viperin

, 2014
Human viperin is known as an interferon (IFN)-inducible antiviral protein and localizes to endoplasmic reticulum (ER) via its N-terminal amphipathic alpha-helix. Little is known about subcellular localization of fish viperin.
Zhang, Yi-Bing, Wang, Bing, Gui, Jian-Fang, Liu, Ting-Kai   +3 more
core   +1 more source