Results 51 to 60 of about 191,821 (303)
Subcellular Imaging of Voltage and Calcium Signals Reveals Neural Processing In Vivo [PDF]
Cell, 2016 A mechanistic understanding of neural computation requires determining how information is processed as it passes through neurons and across synapses. However, it has been challenging to measure membrane potential changes in axons and dendrites in vivo.
Helen H, Yang +5 more
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Application of triphenylphosphonium salt in tumor diagnosis and treatment
上海师范大学学报. 自然科学版Subcellular targeted therapy is a new research direction of tumor therapy. It can cause apoptosis by first damaging subcellular organelles or affecting their surrounding environment.
ZHANG Haifeng, AN Lu
doaj +1 more source
Attentional BiLSTM and Prototype Networks for lncRNA Subcellular Localization Prediction [PDF]
Jisuanji gongchengLong non-coding RNA (lncRNA) are crucial in many cellular life processes, and their subcellular localization can provide key information for their functional identification.
SUN Rongneng, LIU Lin, KANG Yuanzhao
doaj +1 more source
Protocol to determine the subcellular localization of protein interactions in murine keratinocytes
STAR Protocols, 2023 Summary: Protein activities and interactions are determined by their subcellular localization. Elucidating the network of protein-protein interactions at a spatial resolution is essential for understanding the complexity of protein functions, their ...
Lisa Müller
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Nanoparticle surface functionality dictates cellular and systemic toxicity
, 2017 Engineered nanoparticles (NPs) have opened new frontiers in therapeutics and diagnostics in recent years. The surface functionality of these nanoparticles often predominates their interactions with various biological components of human body, and proper ...
Morteza Mahmoudi +31 more
core +1 more source
IMPROVING THE SPEED AND OPTICAL SECTIONING OF FLUORESCENCE MICROSCOPY TECHNIQUES FOR BIOPHYSICAL ANALYSIS OF SUBCELLULAR PROCESSES [PDF]
, 2019 This dissertation focuses on novel fluorescence microscopy techniques and the biophysical analysis of cell biology enabled by such techniques. Modern cell biology research benefits greatly from the ability to accurately visualize the inner workings of ...
Giannini, John
core +1 more source
Subcellular Recruitment of Fibrillarin to Nucleoplasmic Proteasomes: Implications for Processing of a Nucleolar Autoantigen [PDF]
Molecular Biology of the Cell, 2002 A prerequisite for proteins to interact in a cell is that they are present in the same intracellular compartment. Although it is generally accepted that proteasomes occur in both, the cytoplasm and the nucleus, research has been focusing on cytoplasmic protein breakdown and antigen processing, respectively.
Min, Chen +5 more
openaire +2 more sources