Results 71 to 80 of about 7,584 (205)

A role for subchondral bone changes in the process of osteoarthritis; a micro-CT study of two canine models

BMC Musculoskeletal Disorders, 2008
Background This study evaluates changes in peri-articular bone in two canine models for osteoarthritis: the groove model and the anterior cruciate ligament transection (ACLT) model.
van Osch Gerjo JVM, Lafeber Floris PJG, Intema Femke, Sniekers Yvonne H, van Leeuwen Johannes PTM, Weinans Harrie, Mastbergen Simon C   +6 more
doaj   +1 more source

Next‐Generation Paleopathology: Using Commercial AI in Bioarchaeological Diagnosis

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT Artificial intelligence encompasses computational systems capable of performing cognitive functions such as learning, reasoning, and problem‐solving. Within this domain, generative AI and large language models such as ChatGPT, Gemini, and Copilot have shown significant potential in clinical diagnostics.
Jessica Mongillo, Giulia Vescovo, Giulia Manzo, Nicoletta Zedda, Barbara Bramanti   +4 more
wiley   +1 more source

Subchondral Bone Loss Following Orthodontically Induced Cartilage Degradation In The Mandibular Condyles Of Rats

, 2011
Osteoarthritis (Oa) Is A Degenerative Joint Disease Generally Characterized By Progressive Cartilage Degradation And Subchondral Bone Changes. Subchondral Bone Changes Have Been Proposed To Initiate Or Accompany With Cartilage Degradation In Oa.
Mei-Qing Wang, Shi-Bin Yu, Xiao-Dong Liu, Liu, X-D, Jiao, K, Jun Wang, Wang, J, Niu, L-N, Yu, S-B, Juan Dai, Li-Na Niu, Wang, M-Q, Dai, J, Kai Jiao   +13 more
core   +1 more source

Monosodium iodoacetate-induced subchondral bone microstructure and inflammatory changes in an animal model of osteoarthritis

Open Life Sciences, 2022
The monosodium iodoacetate (MIA)-induced osteoarthritis (OA) may lead to cartilage degeneration and histopathological lesions. However, the correlation between inflammatory reaction and subchondral bone remodeling in a rodent osteoarthritic model is ...
Bao Zheming, Chen Mengli, Li Chen, Shan Qing, Wang Yichen, Yang Wenshan   +5 more
doaj   +1 more source

Soluble Epoxide Hydrolase Inhibition Regulates Septoclast Activity to Promote Long Bone Growth and Fracture Healing by Enhancing Endothelial‐to‐Mesenchymal Notch Signalling

Cell Proliferation, EarlyView.
The sEH inhibitor TPPU upregulates endothelial HIF‐1α, activating the NOTCH signalling pathway between endothelial cells and mesenchymal stem cells. This promotes the differentiation and formation of FABP5+ septoclasts, enhances their participation in endochondral ossification, and ultimately improves longitudinal bone growth and fracture healing ...
Weixian Chen, Liangliang Liu, Xumeng Wang, Juanjuan Li, Jingyi Zhang, Xiaoli Shi, Qing Sun, Xu Chang, Jing Zhang, Jie Zhao, Fu Wang   +10 more
wiley   +1 more source

045 SUBCHONDRAL BONE TRABECULAR INTEGRITY PREDICTS AND CHANGES CONCURRENTLYWITH OSTEOARTHRITIS PROGRESSION

Osteoarthritis and Cartilage, 2010
045 – Table 1. Prediction of osteoarthritis progression using subchondral bone trabecular integrity medial mJSW (p=0.029). Baseline BTI was also predictive of OA progression over 12 months based on change in medial JSA (p=0.007). In the reference group, there was no significant change in either outcome variable and no association with bone trabecular ...
Virginia, K., Feng, S., Wang, S., White, S., Ainslie, M., Hellio Le Graverand-Gastineau, M.-P., Brett, A., Charles, C.   +7 more
openaire   +1 more source

Effects of treadmill running with different intensity on rat subchondral bone

Scientific Reports, 2017
Subchondral bone (SB) is recognized as a key factor in normal joint protection, not only does it provide a shock absorbing and supportive function for the cartilage, but it may also be important for cartilage metabolism.
Zhe Li, Sheng-Yao Liu, Lei Xu, Shao-Yong Xu, Guo-Xin Ni   +4 more
doaj   +1 more source

The Effects of Dietary Loading on Chondrocytes Transdifferentiation During Postnatal Maxillary Growth

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Background The mid‐palatal suture is a key growth site for transverse maxillary expansion, yet the cellular mechanisms governing its postnatal development and response to mechanical loading remain poorly defined. This study investigated the contribution of chondrocyte‐derived osteogenesis to maxillary bone formation and the influence of ...
Michael Stark, Paria Dehghanian, Ying Liu, LouisBruno Ruest, Matthew J. Kesterke, Yan Jing   +5 more
wiley   +1 more source

Assessment of tibial fracture healing with dual energy X-ray absorptiometry: influence of metallic implants at the fracture site [PDF]

, 1995
Evaluation of the progress of fracture healing traditionally combines manual fracture manipulation with a visual radiographic assessment. This approach can lead to satisfactory healing, but trouble can ensue when the type of fixation compromises the ...
Cattermole, Howard Charles
core  

Can Knee Arthroscopy Be Considered Entirely Safe for Patients Over 50 Years Old With no Risk of Osteonecrosis? Case Series and Literature Review on Post‐Artrhoscopy Osteonecrosis of the Knee (PAONK)

Orthopaedic Surgery, Volume 17, Issue 5, Page 1378-1388, May 2025.
Post‐arthroscopy osteonecrosis is a rare complication occurring in 0.82% of cases, primarily affecting patients over 50 with degenerative meniscal tears. Early detection through MRI and conservative treatment, including bisphosphonates and weight‐bearing avoidance, proved effective in most cases, while some required surgical intervention.
Panagiotis Ntagiopoulos, Georgios Kalinterakis, Pierrenzo Pozzi, Dimitris Fligkos, George Themistocleous, Sotirios Themistokleous, Triantafyllia Dimou, Riccardo Compagnoni, Paolo Ferrua, Pietro Simone Randelli   +9 more
wiley   +1 more source