Results 81 to 90 of about 558,914 (188)

Mucuna pruriens as a Sustainable Functional Food: Applications From Seed to Product

Modern Agriculture, Volume 4, Issue 2, December 2026.
This review highlights Mucuna pruriens as a nutrient‐rich legume with significant nutritional, therapeutic, and agricultural value. Its protein‐rich seeds contain essential minerals and L‐DOPA, but high antinutritional compounds require effective processing before consumption.
Crossby Osei Tutu, Reuben Acheampong, Papa Toah Akonor, Bernard Kwabena Asiedu, Rexford Obeng, Anthonia Helga Andoh‐Odoom, Dora Duah‐Bisiw, Jacob Ulzen, Michael Wiafe‐Kwagyan, Nii Korley Kortei, Justice Owusu‐Bempah   +10 more
wiley   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, Volume 46, Issue 11, Page 3868-3881, November 2026.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source

Subchronic inhalation toxicity of gold nanoparticles

Particle and Fibre Toxicology, 2011
Background Gold nanoparticles are widely used in consumer products, including cosmetics, food packaging, beverages, toothpaste, automobiles, and lubricants.
Chung Yong, Han Beom, Jeong Jayoung, Jeon Ki, Yoon Jin, Ryu Hyeon, Song Kyung, Song Moon, Park Jung, Ji Jun, Sung Jae, Chang Hee, Lee Ji, Kim Dong, Kelman Bruce J, Yu Il   +15 more
doaj   +1 more source

Tannic Acid Mitigates Monosodium Glutamate‐Induced Cortical Damage by Modulating Synaptic and Calcium‐Related Gene and Protein Expression

Journal of Applied Toxicology, Volume 46, Issue 11, Page 4099-4111, November 2026.
ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac, Enver Fehim Koçpinar, Hamid Ceylan   +2 more
wiley   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, Volume 13, Issue 57, 14 October 2026.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Investigation for subchronic oral toxicity and evaluation of analgesic activities of Stephania tetrandra S. Moore liquid extract in experimental animals

Vietnam Journal of Science, Technology and Engineering
This research evaluates subchronic toxicities and analgesic effects of Stephania tetrandra S. Moore (S. tetrandra) liquid extract through oral administration in experimental animals. Over 4 weeks of subchronic toxicity research, S.
Thanh Mai Phuong, Trang Tran Thi Thu, Khanh Do Thi Hong, Ngoc Tran Thi Hong, Dat Tran Tien, Trang Nguyen Thi Mai, Minh Phan Hong   +6 more
doaj   +1 more source

Acute and subchronic toxicity study of the water extract from root of Citrus aurantifolia (Christm. et Panz.) Swingle in rats [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2007
Acute and subchronic toxicities of the water extract from the roots of Citrus aurantifolia were studied in both male and female rats. Oral administration of the extract at a single dose of 5,000 mg/kg body weight (5 male, 5 female) did not produce signs ...
Kanjana Jaijoy, Nadthaganya Suwanlikhid, Anongnad Ngamjariyawat, Amornnat Thuppia, Nirush Lertprasertsuke, Umarat Srisawat, Siharat Chunlaratthanaphorn   +6 more
doaj  

The acute, subchronic and reproductive toxicity of guan-mu-tong (caulis aristolochiae manshuriensis) and ma-dou-ling (fructus aristolochiae). [PDF]

, 1997
by Chan Po Wai.Thesis (M.Phil.)--Chinese University of Hong Kong, 1997.Includes bibliographical references (leaves 110-117).Table of Contents --- p.iAbbreviations --- p.ivAbstract --- p.vList of Figures --- p.viiList of Tables --- p.xiChapter ...

core  

Acute and subchronic oral toxicity of oil palm puree in Sprague–Dawley rats

, 2020
Palm puree is rich in antioxidants and is produced via blending various proportions of mesocarp fibre and crude palm oil. The aim of this study was to assess the acute and subchronic toxicity of palm puree in male and female Sprague–Dawley rats.
Ong, Augustine, Huzwah Khaza’ai, Chang, Sui Kiat, Zaida Zainal, Augustine Ong, Choo Yuen May, Sui Kiat Chang, Afiqah Abdul Rahim, Zainal, Zaida, Abdul Rahim, Afiqah, Khaza'ai, Huzwah, Choo, Yuen May   +11 more
core   +1 more source

CDK4/MERCs/PINK1 Axis Drives PFOA/HFPO‐TA‐Induced Cardiac Senescence via Mitophagy Defect and cGAS‐STING Activation: In Vitro Amelioration by Cycloastragenol

Advanced Science, Volume 13, Issue 56, 9 October 2026.
The present study demonstrated that PFOA and HFPO‐TA exposure suppressed CDK4, disrupted MERCs and impaired PINK1/Parkin‐mediated mitophagy, thereby accelerating cardiac senescence, whereas CAG effectively reversed these pathological changes in vitro. Our findings identify CDK4 as a critical regulator bridging mitophagy defects and cardiac senescence ...
Nuo‐Wa Li, Jun‐Ze Jiang, Ying‐Ying Liu, Tian‐Tian Zhang, Kanwar Kumar Malhi, Xin Yao, Jin‐Long Li   +6 more
wiley   +1 more source