Results 121 to 130 of about 9,711 (221)

Design, Synthesis, and Biological Evaluation of Chiral Urea and Thiourea Derivatives as Multitarget‐Directed Anti‐Alzheimer Agents

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A series of novel chiral urea and thiourea compounds were designed as multitarget‐directed ligands for Alzheimer's disease and evaluated against hAChE, hBChE, and hMAO‐B, with exploratory assessment of HSD10. These chiral compounds were synthesized and fully characterized, and their enantiopurity was confirmed via HPLC.
Sule Erol Gunal   +10 more
wiley   +1 more source

Is Blood Thicker Than Water? The Influence of Kin Within a Bull Shark Social Network

open access: yesEcology and Evolution, Volume 16, Issue 8, August 2026.
This study investigates how kinship (“kinfluence”) shapes social structure in an aggregation of adult bull sharks in Fiji by integrating genomic relatedness, pedigree reconstruction, and detailed behavioral data. It reveals that while genetic relatedness has a small but significant influence on social behavior, especially among males, kin‐category ...
Natasha D. Marosi   +4 more
wiley   +1 more source

Effects of Lactobacillus‐Mediated Functionalization of Dendrobium officinale Polysaccharides: A Study From Physicochemical Properties and Structural Changes to Anti‐Inflammatory Activity

open access: yeseFood, Volume 7, Issue 4, August 2026.
Lactic acid bacteria (LAB) fermentation cleaves specific glycosidic bonds in Dendrobium officinale polysaccharides (DOPs), reducing molecular weight and enhancing anti‐inflammatory activity through regulation of inflammatory cytokines, oxidative stress, and intestinal barrier function.
Dingding Hong, Hui Ye, Xiaojun Huang
wiley   +1 more source

Farming in the shadows of Rome: A multi‐proxy palaeoenvironmental record from Loch Clunie—Perthshire

open access: yesJournal of Quaternary Science, Volume 41, Issue 6, Page 915-932, August 2026.
ABSTRACT Roman impacts on local society is a subject of international significance. Loch Clunie, Perthshire, lies only 5.4 km from Inchtuthil, the only Roman legionary fortress in Scotland, and contains two crannogs and a probable lakeside hillfort. Despite this proximity and the likelihood of local–Roman interaction, these sites remain unexcavated ...
Samantha E. Jones   +6 more
wiley   +1 more source

Effect of gamma irradiation and storage days on physicochemical, sensory, and microbial quality of pineapple (Ananas comosus) fresh cut under refrigeration

open access: yesJSFA reports, Volume 6, Issue 8, Page 292-300, August 2026.
Abstract Background Fresh‐cut pineapple is increasingly consumed for its convenience and nutritional value; however, minimal processing accelerates quality deterioration and microbial growth, resulting in substantial postharvest losses. Gamma irradiation is recognized as a nonthermal preservation technique, but limited information exists regarding its ...
Maraj Miah   +6 more
wiley   +1 more source

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