Results 101 to 110 of about 22,248,138 (428)

Tilt in quadratic gravity [PDF]

open access: yesVolume 84, article number 843, (2024), European Physical Journal C
In this work, tilted source solutions in both Einstein-Hilbert General Relativity (GR) and Quadratic Gravity (QG) for the anisotropic Bianchi V model are addressed. Since the excellent CMBR match of Starobinsky's inflation with Planck's team measurements data, QG has acquired a prominent status in the effective sense, for sufficiently strong gravity ...
arxiv   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Immunohistochemical analysis of peptide pathways possibly related to pain and analgesia: enkephalin and substance P

open access: yes, 1977
The distribution of Met-enkephalin- and substance P-immunoreactive neurons was studied by indirect immunofluorescence in some areas related to pain and analgesia.
T. Hökfelt   +4 more
semanticscholar   +1 more source

Substance P modulates colitis-associated fibrosis.

open access: yesAmerican Journal of Pathology, 2010
Substance P (SP) and the neurokinin-1 receptor (NK-1R) are involved in the development of colitis and mucosal healing after colonic inflammation. We studied whether SP modulates colonic fibrosis by using a chronic model of trinitrobenzenesulfonic acid ...
H. Koon   +9 more
semanticscholar   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Expression of gastrin-releasing peptide by excitatory interneurons in the mouse superficial dorsal horn [PDF]

open access: yes, 2014
Background: Gastrin-releasing peptide (GRP) and its receptor have been shown to play an important role in the sensation of itch. However, although GRP immunoreactivity has been detected in the spinal dorsal horn, there is debate about whether this ...
Gutierrez-Mecinas, Maria   +2 more
core   +1 more source

Quantum Maxwell's Demon in Thermodynamic Cycles [PDF]

open access: yes, 2010
We study the physical mechanism of Maxwell's Demon (MD) helping to do extra work in thermodynamic cycles, by describing measurement of position, insertion of wall and information erasing of MD in a quantum mechanical fashion. The heat engine is exemplified with one molecule confined in an infinitely deep square potential inserted with a movable solid ...
arxiv   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Positive associations between consumerism and tobacco and alcohol use in early adolescence: cross-sectional study [PDF]

open access: yes, 2012
<p>Background: There is concern about the negative impact of modern consumer culture on young people's mental health, but very few studies have investigated associations with substance use.
Bhaskar, A., Hunt, K., Sweeting, H.N.
core   +1 more source

Tear neuropeptides are associated with clinical symptoms and signs of dry eye patients

open access: yesAnnals of Medicine
Purpose To evaluate levels of 3 tear-soluble neuropeptides in dry eye patients and to identify the correlations with clinical signs and symptoms.Methods A total of 16 dry eye patients and 12 healthy volunteers were enrolled.
Yirou Zhang   +6 more
doaj   +1 more source

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