Results 61 to 70 of about 2,081,661 (298)

Combined Unilateral Blockade of Cholinergic, Peptidergic, And Serotonergic Receptors in The Ventral Respiratory Column Does Not Affect Breathing in Awake Or Sleeping Goats [PDF]

, 2015
Previous work in intact awake and sleeping goats has found that unilateral blockade of excitatory inputs in the ventral respiratory column (VRC) elicits changes in the concentrations of multiple neurochemicals, including serotonin (5-HT), substance P ...
Forster, Hubert, Hodges, Matthew, Langer, Thomas, Miller, Justin Robert, Muere, Clarissa, Neumueller, Suzanne, Olesiak, Samantha, Pan, Lawrence   +7 more
core   +2 more sources

A Programmable Nanoreactor Orchestrates Cascade of DNA Sensing to Amplify cGAS‐STING Activation for Cancer Immunotherapy

Advanced Science
The cGAS‐STING pathway, a critical cytosolic DNA‐sensing mechanism in innate immunity, holds significant promise for cancer immunotherapy. However, conventional DNA‐damaging therapies lack tumor specificity and cause damage to normal tissue. Furthermore,
Shuang Liang, Yiwei Tian, Feiyu Zhao, Yue Han, Kongshuo Ma, Linna Hai, Kaiqing Yun, Yueyang Zhao, Siqi Zhang, Ziyi Zhang, Yuxuan Peng, Kuan Hu, Jing Zhong, Bai Xiang, Zhaohui Wang   +14 more
doaj   +1 more source

Incorporation of ROS-Responsive Substance P-Loaded Zeolite Imidazolate Framework-8 Nanoparticles into a Ca2+-Cross-Linked Alginate/Pectin Hydrogel for Wound Dressing Applications

International Journal of Nanomedicine, 2020
Yiming Zhu, 1 Zuochao Yao, 2 Yushu Liu, 3 Wen Zhang, 2 Lele Geng, 2 Tao Ni 2 1Department of General Surgery, Shanghai Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Huangpu, Shanghai, China; 2Department of Plastic and
Zhu Y, Yao Z, Liu Y, Zhang W, Geng L, Ni T   +5 more
doaj  

Expression of substance P and neurokinin-1 receptor in nasopharyngeal carcinoma and their clinical significance

Di-san junyi daxue xuebao, 2020
Objective To investigate the expression of substance P (SP) and its receptor, neurokinin-1 receptor (NK-1R), in nasopharyngeal carcinoma (NPC) tissues and their correlation with the clinicopathological parameters of the patients.
ZHANG Yu, YANG Yucheng, YANG Kun, FENG Dandan, HUANG Jiangju   +4 more
doaj   +1 more source

Gender Differences in Smoking Among an Urban Emergency Department Sample. [PDF]

, 2019
BackgroundUrban emergency department (ED) patients have elevated smoking and substance use compared with the general population. We analyzed gender differences in smoking among an urban ED sample and assessed the contribution of substance use ...
Alter, Harrison J, Caetano, Raul, Cunradi, Carol B, Lee, Juliet, Pagano, Anna   +4 more
core  

Complexity of childhood sexual abuse: predictors of current post-traumatic stress disorder, mood disorders, substance use, and sexual risk behavior among adult men who have sex with men [PDF]

, 2015
Men who have sex with men (MSM) are the group most at risk for HIV and represent the majority of new infections in the United States. Rates of childhood sexual abuse (CSA) among MSM have been estimated as high as 46 %.
Baker, Joshua S., Boroughs, Michael S., Dale, Sannisha K., Ironson, Gail H., O'Cleirigh, Conall, Safren, Steven A., Shipherd, Jillian C., Taylor, S. Wade, Valentine, Sarah E., Wilner, Julianne G.   +9 more
core   +1 more source

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

The effect of using assessment instruments on substance-abuse outpatients' adherence to treatment: a multi-centre randomised controlled trial [PDF]

, 2011
Background: Drop-out is an important problem in the treatment of substance use disorder. The focus of this study was to investigate the effectiveness of within treatment assessment with feedback directly to patients with multiple substance use disorder ...
Raes, Veerle, De Jong, Cor AJ, De Bacquer, Dirk, Broekaert, Eric, De Maeseneer, Jan   +4 more
core   +3 more sources

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Substance P and neprilysin in chronic pancreatitis [PDF]

, 2012
Background/Aims: We aimed to analyze substance P (SP) and neprilysin (NEP), the membrane metallopeptidase that degrades SP, in chronic pancreatitis (CP).
Bassi, Claudio, Büchler, Markus W., Di Mola, Fabio Francesco, Di Sebastiano, Pierluigi, Friess, Helmut, Giese, Natalia, Mascetta, Giuseppe, Selvaggi, Federico, Tavano, Francesca   +8 more
core   +3 more sources