Results 51 to 60 of about 673,739 (304)
Association of Mental Disorders in Early Adulthood and Later Psychiatric Hospital Admissions and Mortality in a Cohort Study of More Than 1 Million Men [PDF]
Context Mental disorders have been associated with increased mortality, but the evidence is primarily based on hospital admissions for psychoses. The underlying mechanisms are unclear.
Batty, G David +5 more
core +1 more source
Frequency of Parental Psychopathology in Children with Attention Deficit Hyperactivity Disorder [PDF]
Parental mental health concerns place children at a significantly greater risk of lower social, psychological and physical health than children in families not affected by mental illness.
Bhat, SM, Latha, KS, Nair, RB
core +1 more source
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra +3 more
wiley +1 more source
Current Concepts on Drug Abuse and Dependence [PDF]
Drug addiction is a complex disease characterized by compulsive and uncontrollable desire to seek and consume the drug. In time, drug-related terminology has undergone many changes, arising from the deepening of the mechanisms of action, but also about ...
Baconi, Daniela Luiza +5 more
core +3 more sources
NOP-Related Mechanisms in Substance Use Disorders [PDF]
Nociceptin/orphanin FQ (N/OFQ) is a 17 amino acid peptide that was deorphanized in 1995 and has been widely studied since. The role of the N/OFQ system in drug abuse has attracted researchers' attention since its initial discovery. The first two scientific papers describing the effect of intracranial injection of N/OFQ appeared 20 years ago and ...
Ciccocioppo R. +5 more
openaire +2 more sources
Declines in prevalence of adolescent substance use disorders and delinquent behaviors in the USA: A unitary trend? [PDF]
BackgroundDownward trends in a number of adolescent risk behaviors including violence, crime, and drug use have been observed in the USA in recent years.
Agrawal, Arpana +7 more
core +2 more sources
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
Heroin-piracetam mixture: suggested mechanisms of action and risks of misinterpretation for drug users [PDF]
Piracetam is a positive allosteric modulator of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor that has been frequently used in the treatment of cognitive disorders.
Cappelletti, Simone +4 more
core +1 more source
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda +15 more
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source

