Results 71 to 80 of about 673,739 (304)

Pattern of psychoactive substance use by students - Ribeirão Preto

open access: yesSaúde em Debate
The aim was to analyze the use of psychoactive substances among students in their final year of middle school and high school in Ribeirão Preto and reflect on the pattern of psychoactive drug use based on epidemiological studies conducted over the last ...
Margarita Antonia Villar Luis   +4 more
doaj   +1 more source

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

open access: yes
Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari   +9 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Event-related functional magnetic resonance imaging of reward-related brain circuitry in children and adolescents [PDF]

open access: yes, 2007
BACKGROUND: Functional disturbances in reward-related brain systems are thought to play a role in the development of mood, impulse, and substance abuse disorders. Studies in non-human primates have identified brain regions, including the dorsal / ventral
May, John Christopher
core  

The 1 % of the population accountable for 63 % of all violent crime convictions [PDF]

open access: yes, 2013
PURPOSE: Population-based studies on violent crime and background factors may provide an understanding of the relationships between susceptibility factors and crime.
Anckarsater, Henrik   +6 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Bullying involvement and substance use among Brazilian adolescent students

open access: yesRevista Panamericana de Salud Pública, 2018
Objective. Although bullying involvement has been associated with adolescent substance use, most of this evidence comes from high-income countries. Little is known about substance use among perpetrator-victims in low- and middle-income countries.
Natalia Woolley, James Macinko
doaj   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Risk factors for incidence and persistence of disability in chronic major depression and alcohol use disorders: longitudinal analyses of a population-based study [PDF]

open access: yes, 2014
BackgroundMajor depression and alcohol use disorders are risk factors for incidence of disability. However, it is still unclear whether a chronic course of these health conditions is also prospectively associated with incidence of disability.
Ayuso-Mateos, J.   +4 more
core   +1 more source

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