Results 81 to 90 of about 673,739 (304)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Understanding Health Risks for Adolescents in Protective Custody [PDF]

open access: yes, 2019
Children in child welfare protective custody (e.g., foster care) are known to have increased health concerns compared to children not in protective custody. The poor health documented for children in protective custody persists well into adulthood; young
Beal, Sarah J.   +3 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Prevalence and risk factors for drug use and dependence in university students from Medellín, Colombia, 2009

open access: yesRevista Facultad Nacional de Salud Pública, 2012
Objective: to determine the prevalence and risk factors for druguse and dependence among students at a university in Medellín,Colombia. Methodology: an analytical study in which 1264students were surveyed using a random sampling, stratified bythe number ...
Andrés F. Tirado O   +5 more
doaj  

Attention to the people with substance-related disorders at spanish prisons [PDF]

open access: yes, 2017
Trabajo fin de grado en EnfermeríaIntroducción: El consumo de drogas genera alteraciones a nivel biopsicosocial y puede dar lugar al ingreso en penitenciarías.
Alonso Valero, Irene   +1 more
core  

Housing situation and healthcare for patients in a psychiatric centre in Berlin, Germany: a cross-sectional patient survey [PDF]

open access: yes, 2019
OBJECTIVE: To determine the housing situation among people seeking psychiatric treatment in relation to morbidity and service utilisation. DESIGN: Cross-sectional patient survey.
Bermpohl, Felix   +11 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Caffeine consumption of medical students in Korea: amount and symptoms based on a 2023 survey [PDF]

open access: yesKorean Journal of Medical Education
Purpose To investigate the form and level of daily caffeine intake recommended above 400 mg in medical students expected to consume caffeinated beverages to enhance their performance.
Seong Woo Choi   +6 more
doaj   +1 more source

A Roadmap for Integrating Neuroscience into Addiction Treatment:A Consensus of the Neuroscience Interest Group of the International Society of Addiction Medicine [PDF]

open access: yes, 2019
Although there is general consensus that altered brain structure and function underpins addictive disorders, clinicians working in addiction treatment rarely incorporate neuroscience-informed approaches into their practice.
Arunogiri, Shalini   +25 more
core   +7 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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