Results 51 to 60 of about 1,829,207 (256)
A case of neuroleptic malignant syndrome on withdrawal of benzhexol [PDF]
, 2010 The neuroleptic malignant syndrome is a rare and potentially lethal reaction which is usually associated with the use of medications with antidopaminergic properties.
Ferry, Peter +2 more
core
Alcohol Withdrawal Syndrome [PDF]
, 2016 Alcohol withdrawal syndrome is a cluster of symptoms occurring when someone detoxes from alcohol.
Chandran, Rabindran, Gedam, D Sharad
core +1 more source
Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy
Advanced Science, EarlyView.By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng +16 more
wiley +1 more source
Advanced Science, EarlyView.A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li +9 more
wiley +1 more source
A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control
Advanced Science, EarlyView.Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias +23 more
wiley +1 more source
Appendicitis in a patient with psychiatric problem and drug withdrawal symptoms.
Iranian Journal of Psychiatry, 2010 Physical disorders can be seen in psychiatric patients. In addition, a delayed diagnosis can cause a serious complication of the physical disorder among such patients.
Viroj Wiwanitkit
doaj
The Use of Benzodiazepines in the Elderly Population: Epidemiology, Risks and Withdrawal Management [PDF]
Eurasian Journal of Family MedicineBenzodiazepines remain one of the most commonly prescribed medications. Approximately 9% of adults in the United States aged 65 years or above are benzodiazepine users.
Zuzanna Hertz, Szymon Barczak
doaj +1 more source
Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape
Advanced Science, EarlyView.Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim +12 more
wiley +1 more source
An interesting presentation of psychotic catatonia in an elderly patient with alcohol dependence
Journal of Geriatric Mental Health, 2019 Catatonia is a neuropsychiatric syndrome with multifactorial etiopathogenesis. It can be seen in patients with alcohol dependence in the context of withdrawal in the presence of comorbid psychiatric disorders (substance induced or independent) or as a ...
Migita Michael Dcruz +3 more
doaj +1 more source
Advanced Science, EarlyView.A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang +10 more
wiley +1 more source