Extended Anatomical Grading in Diffuse Axonal Injury Using MRI: Hemorrhagic Lesions in the Substantia Nigra and Mesencephalic Tegmentum Indicate Poor Long-Term Outcome [PDF]
, 2016 Sami Abu Hamdeh +6 more
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Corrigendum to: Spatiotemporal changes in substantia nigra neuromelanin content in Parkinson’s disease [PDF]
, 2020 openalex +1 more source
Characteristics of Swallowing Function in People with Parkinson's Disease: A Scoping Review
Movement Disorders, EarlyView.Abstract Background Most individuals with Parkinson's disease (PD) develop dysphagia during the course of their disease. It is crucial to comprehensively understand swallowing characteristics specific to PD for effective treatment. Objectives To systematically analyze and synthesize swallowing characteristics in people with PD compared with healthy ...
Kerstin Erfmann +6 more
wiley +1 more source
Movement Disorders, EarlyView.Background Accurate temporal prediction, essential for adaptive motor behavior, relies on corticobasal ganglia circuits. In Parkinson's disease (PD), both motor and non‐motor functions are impaired. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) effectively alleviates motor symptoms, but its effects on non‐motor domains, like temporal ...
Rebecca Burke +5 more
wiley +1 more source
Reply: To Exercise at High Intensity Heart Rate or Not to Exercise at High Intensity Heart Rate?
Movement Disorders Clinical Practice, EarlyView.
Lennard I. Boon +2 more
wiley +1 more source
Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids
Movement Disorders, EarlyView.Abstract Neurodegenerative diseases are pathological states characterized by progressive alterations in brain homeostasis during aging. Synucleinopathies, including Parkinson's disease and dementia with Lewy bodies, are defined neuropathologically by the accumulation of inclusions known as Lewy bodies and Lewy neurites.
Manuel Flores‐León, Tiago F. Outeiro
wiley +1 more source
Scientific ReportsNigrostriatal dopaminergic degeneration in alpha-synucleinopathies is indirectly reflected by low dopamine transporter (DaT) uptake through [123I]FP-CIT-SPECT. Bulk magnetic susceptibility ( $$\chi$$ ) in the substantia nigra, from MRI-based quantitative
Oliver C. Kiersnowski +17 more
doaj +1 more source
Parkinson's Disease Patient‐Specific Striatum Organoids Show Hallmarks of Increased Inflammation
Movement Disorders, EarlyView.Abstract Background Dopaminergic neurons from the substantia nigra pars compacta project their axons into the dorsal striatum, forming the nigrostriatal pathway. In Parkinson's disease (PD), dopaminergic terminals degenerate in the striatum, leading to dopamine depletion, which in turn causes alterations in the basal ganglia circuits that are essential
Kyriaki Barmpa +11 more
wiley +1 more source
Protocols for "Functional efficacy of the MAO-B inhibitor safinamide in murine substantia nigra pars compacta dopaminergic neurons in vitro: a comparative study with tranylcypromine" v1 [PDF]
Nicola Biagio Mercuri
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