Results 121 to 130 of about 123,595 (337)

High-Resolution Proteomics Unravel a Native Functional Complex of Cav1.3, SK3, and Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels in Midbrain Dopaminergic Neurons

open access: yesCells
Pacemaking activity in substantia nigra dopaminergic neurons is generated by the coordinated activity of a variety of distinct somatodendritic voltage- and calcium-gated ion channels. We investigated whether these functional interactions could arise from
Maya Belghazi   +6 more
doaj   +1 more source

Intraputaminal Delivery of Adeno‐Associated Virus Serotype 2–Glial Cell Line–Derived Neurotrophic Factor in Mild or Moderate Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Glial cell line–derived neurotrophic factor (GDNF) is required for development and survival of dopaminergic neurons. A previous trial evaluating lower‐dose adeno‐associated virus serotype 2–GDNF (AAV2‐GDNF) bilateral intraputaminal infusion in participants with advanced Parkinson's disease (PD) achieved 26% mean putaminal coverage ...
Amber D. Van Laar   +10 more
wiley   +1 more source

Soemmerring and the Substantia Nigra [PDF]

open access: yesMedical History, 1968
J. B. Carman   +2 more
openaire   +2 more sources

Distinct progression pattern of susceptibility MRI in the substantia nigra of Parkinson's patients

open access: yesMovement Disorders, 2018
G. Du   +7 more
semanticscholar   +1 more source

Pathophysiological Role of Primary Motor Cortex in Essential Tremor

open access: yesMovement Disorders, EarlyView.
Abstract Background Essential tremor (ET) is one of the most prevalent movement disorders. However, the complete understanding of ET pathophysiology remains elusive. Objective To explore the pathophysiological role of primary motor cortex (M1) in ET, specifically exploring its neurophysiological changes and their correlation with voluntary motor ...
Daniele Birreci   +10 more
wiley   +1 more source

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