Results 131 to 140 of about 76,030 (307)

Table_1_Effects of Chemogenetic Inhibition of D1 or D2 Receptor-Containing Neurons of the Substantia Nigra and Striatum in Mice With Tourette Syndrome.xlsx

, 2021
Lixue Lin (7496957), Yuye Lan (11816234), He Zhu (1391056), Lingling Yu (2886005), Shuang Wu (148427), Wangyixuan Wan (11816237), Yang Shu (528866), Hongchun Xiang (7496960), Tengfei Hou (7496966), Hong Zhang (25820), Yan Ma (88810), Wen Su (332346), Man Li (81239)   +12 more
openalex   +2 more sources

Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease

Neuroprotection, EarlyView.
Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García, Edgar Alvarado, Alejandro Cuevas, Laura Valverde, Eduardo Salinas, Kevin O'Hara‐Veintimilla, María Cruz Rodríguez‐Oroz, Miguel Germán Borda   +7 more
wiley   +1 more source

Immunoreactive signals of GPR143 in the ventral tegmental area, substantia nigra and their trajectories

, 2018
Kohtaro Takizawa, Motokazu Koga, Daiki Masukawa, Fumio Nakamura, Yoshio Goshima   +4 more
openalex   +2 more sources

GM1 Administration Prevents Alterations in BCL‐2 and Bax Expression in Substantia Nigra Neurons Following MPTP Administration^a [PDF]

, 1998
David W. Anderson, John C. Reed, S Krajewski, J. S. SCHNEIDERB   +3 more
openalex   +1 more source

Coupling CZE, Liquid‐Phase Ion Mobility, to MS/MS for Quantitative Top‐Down Proteomics: Revealing Significant Proteoform Differences Between Healthy and Alzheimer's Disease Brains

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and pathological protein aggregation. Comprehensive quantitative proteomics of brain tissues from AD patients is critical for pursuing a better understanding of the molecular mechanisms that drive AD progression.
Mehrdad Falamarzi Askarani, Fei Fang, Scott E. Counts, Liangliang Sun   +3 more
wiley   +1 more source

Synaptic integration and competition in the substantia nigra pars reticulata-An experimental and in silico analysis. [PDF]

Proc Natl Acad Sci U S A
Thompson WS, Hjorth JJJ, Kozlov A, Thunberg W, Silberberg G, Hellgren Kotaleski J, Grillner S.   +6 more
europepmc   +1 more source

Probing Early α‐Synuclein Oligomers: Insights Into Aggregation Pathways of NACore and preNAC Segments Probed by Trapped Ion‐Mobility Mass Spectrometry and Fluorescence Spectroscopy

PROTEOMICS, EarlyView.
ABSTRACT Misfolding and aggregation of α‐Synuclein (α‐Syn) play a central role in Parkinson's disease (PD), with oligomeric intermediates implicated as key toxic species. Here, we investigate the aggregation of two α‐Syn segments, the NACore (68GAVVTGVTAVA78, WT‐PD1) and the preNAC region (47GVVHGVATVA56, WT‐PD2), using high‐resolution trapped ion ...
Agathe Depraz Depland, Stephanie Mikromanolis, Iuliia Stroganova, Anouk M. Rijs   +3 more
wiley   +1 more source

Dopamine D1 Receptor Immunoreactivity on Fine Processes of GFAP-Positive Astrocytes in the Substantia Nigra Pars Reticulata of Adult Mouse [PDF]

, 2017
Katsuhiro Nagatomo, Sechiko Suga, Masato Saitoh, Masahito Kogawa, Kazuto Kobayashi, Yoshio Yamamoto, Katsuya Yamada   +6 more
openalex   +1 more source

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

Environmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo, Patricia Meade, Irene Jiménez‐Salvador, Carmen Hernández‐Ainsa, Eldris Iglesias, Alba Pesini, Nuria Garrido‐Pérez, Sonia Emperador, David Pacheu‐Grau, Pilar Bayona‐Bafaluy, Eduardo Ruiz‐Pesini   +10 more
wiley   +1 more source

Neuropathologic basis of quantitative susceptibility mapping in the substantia nigra: contributions of tau, pigmented neurons, and iron. [PDF]

Acta Neuropathol
Ono D, Kondrakunta S, Mak E, Przybelski SA, Fought AJ, Schwarz CG, Murray ME, Nguyen A, Reichard RR, Senjem ML, Gunter JL, Jack CR, Miyagawa T, Forsberg LK, Fields JA, Savica R, Ramanan VK, Jones DT, Botha H, Louis EKS, Knopman DS, Graff-Radford NR, Day GS, Ferman TJ, Kremers WK, Lowe VJ, Petersen RC, Boeve BF, Dickson DW, Kantarci K.   +29 more
europepmc   +1 more source