Neuronal Firing and Glutamatergic Synapses in the Substantia Nigra Pars Reticulata of LRRK2-G2019S Mice [PDF]
, 2022 Giacomo Sitzia +2 more
openalex +1 more source
An Unusual Motor OFF in Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.
Shreyashi Jha, Mandar S. Jog
wiley +1 more source
Bipolar Disorder as a Long‐Term Risk Factor for Parkinson's Disease: A Nationwide Case–Control Study
Movement Disorders, EarlyView.Abstract Background Previous studies suggest an association between bipolar disorder (BD) and an increased risk of Parkinson's disease (PD), but the long‐term temporal relationship remains unclear. Particularly, it is unclear whether the risk of PD is influenced by the duration since BD diagnosis.
Elina Jaakkola +5 more
wiley +1 more source
Medial septum differentially regulates dopamine neuron activity in the rat ventral tegmental area and substantia nigra via distinct pathways [PDF]
, 2018 David M. Bortz, Anthony A. Grace
openalex +1 more source
Beyond Pathology: α‐Synuclein Homeostasis and Three Principles to Guide Research
Movement Disorders Clinical Practice, EarlyView.
Alberto J. Espay, Andrew J. Lees
wiley +1 more source
Nuclear Alpha‐Synuclein: Mechanisms and Implications for Synucleinopathies
Movement Disorders, EarlyView.Abstract Alpha‐synuclein (aSyn), historically studied for its synaptic functions and central role in Lewy body pathology, is emerging as a protein with significant nuclear activities relevant to Parkinson's disease (PD) and related synucleinopathies. Recent advances reveal that aSyn dynamically localizes to neuronal nuclei in both health and disease ...
Tiago Fleming Outeiro, David J. Koss
wiley +1 more source
Identification of the isoforms of Ca2+/calmodulin‐dependent protein kinase II and expression of brain‐derived neurotrophic factor mRNAs in the substantia nigra [PDF]
, 2005 Akifumi Kamata +2 more
openalex +1 more source
Characteristics of Swallowing Function in People with Parkinson's Disease: A Scoping Review
Movement Disorders, EarlyView.Abstract Background Most individuals with Parkinson's disease (PD) develop dysphagia during the course of their disease. It is crucial to comprehensively understand swallowing characteristics specific to PD for effective treatment. Objectives To systematically analyze and synthesize swallowing characteristics in people with PD compared with healthy ...
Kerstin Erfmann +6 more
wiley +1 more source
Movement Disorders, EarlyView.Background Accurate temporal prediction, essential for adaptive motor behavior, relies on corticobasal ganglia circuits. In Parkinson's disease (PD), both motor and non‐motor functions are impaired. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) effectively alleviates motor symptoms, but its effects on non‐motor domains, like temporal ...
Rebecca Burke +5 more
wiley +1 more source