Results 161 to 170 of about 133,054 (344)

Endotoxin induces a delayed loss of TH-IR neurons in substantia nigra and motor behavioral deficits

, 2020
Yuxin Liu, Liya Qin, Belinda Wilson, Xuefei Wu, Qian Li, Ann Charlotte Granholm, Fulton T. Crews, Jau‐Shyong Hong   +7 more
openalex   +1 more source

Table_1_Effects of Chemogenetic Inhibition of D1 or D2 Receptor-Containing Neurons of the Substantia Nigra and Striatum in Mice With Tourette Syndrome.xlsx

, 2021
Lixue Lin (7496957), Yuye Lan (11816234), He Zhu (1391056), Lingling Yu (2886005), Shuang Wu (148427), Wangyixuan Wan (11816237), Yang Shu (528866), Hongchun Xiang (7496960), Tengfei Hou (7496966), Hong Zhang (25820), Yan Ma (88810), Wen Su (332346), Man Li (81239)   +12 more
openalex   +2 more sources

Clinical and Imaging Characteristics of Parkinson's Disease with Negative Alpha‐Synuclein Seed Amplification Assay

Movement Disorders, EarlyView.
Abstract Background The cerebrospinal fluid alpha‐synuclein seed amplification assay (CSFasynSAA) detects alpha‐synuclein aggregation in over 90% of individuals with sporadic PD (sPD). However, the clinical characteristics of sPD with negative CSFasynSAA remain undefined.
Sarah M. Brooker, Jacopo Pasquini, Seung Ho Choi, David‐Erick Lafontant, Seyed‐Mohammad Fereshtehnejad, Yashar Zeighami, Piergiorgio Grillo, Giulietta M. Riboldi, Houman Azizi, Roqaie Moqadam, Un Jung Kang, Kelly N.H. Nudelman, Andrew Siderowf, Caroline M. Tanner, Thomas F. Tropea, Tatiana Foroud, Lana M. Chahine, Brit Mollenhauer, Kalpana M. Merchant, Douglas Galasko, Christopher S. Coffey, Roseanne D. Dobkin, Ethan G. Brown, Roy N. Alcalay, Daniel Weintraub, Kenneth Marek, Tanya Simuni, Paulina Gonzalez‐Latapi, Nicola Pavese, Kathleen L. Poston, the Parkinson's Progression Markers Initiative   +30 more
wiley   +1 more source

Study on transcranial sonography in patients with idiopathic rapid eye movement sleep behavior disorder

Chinese Journal of Contemporary Neurology and Neurosurgery, 2016
Objective To investigate the changes of transcranial sonography (TCS) in patients with rapid eye movement sleep behavior disorder (RBD).  Methods Fifteen patients fulfilled the diagnostic criteria of RBD according to International Classification of ...
Xu-dong LI, Shuang XUE, Chun-lei HOU, Shu-hong JIA, Ya-nan QIAO, Zhi ZHOU, Kun WEI, Wen-jing ZHENG, Pei RONG, Jin-song JIAO   +9 more
doaj  

Immunoreactive signals of GPR143 in the ventral tegmental area, substantia nigra and their trajectories

, 2018
Kohtaro Takizawa, Motokazu Koga, Daiki Masukawa, Fumio Nakamura, Yoshio Goshima   +4 more
openalex   +2 more sources

Monoaminergic Networks of Cognitive and Behavioral Symptoms in Early Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is associated with several behavioral and cognitive symptoms, the neurobiological background of which is not yet fully understood. Objectives The aim was to investigate the association between monoamine function and four specific nonmotor symptoms in early PD using the Parkinson's Progression Markers ...
Kalle J. Niemi, Valtteri Kaasinen, Rimona S. Weil, Juho Joutsa   +3 more
wiley   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Synaptic integration and competition in the substantia nigra pars reticulata-An experimental and in silico analysis. [PDF]

Proc Natl Acad Sci U S A
Thompson WS, Hjorth JJJ, Kozlov A, Thunberg W, Silberberg G, Hellgren Kotaleski J, Grillner S.   +6 more
europepmc   +1 more source

Author response: The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons

, 2016
Andrew Lutas, Carolina Lahmann, Magali Soumillon, Gary Yellen   +3 more
openalex   +1 more source

Underlying Mechanisms of the Treatment Efficacy of (R, S)‐Ketamine for Post‐Traumatic Stress Disorder and Depression: A Review

Medicine Advances, EarlyView.
Research shows that (R, S)‐ketamine and its stereoisomers effectively reduce symptoms of post‐traumatic stress disorder (PTSD) and treatment‐resistant depression, with (R)‐ketamine offering similar benefits with fewer side effects. Evidence highlights specific neural circuits and regions, including the dentate gyrus, prefrontal cortex, vCA3, dorsal ...
Thomas Edward Cutting, Richard Evans Hartman   +1 more
wiley   +1 more source