Effect of age on substantia nigra subregions using neuromelanin-sensitive magnetic resonance imaging overlapping on quantitative susceptibility mapping. [PDF]
Kuang C, Liu WV, Li L, Liu C, Zha Y.
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Cerebral iron deposition in the Globus pallidus and Substantia nigra of aging dogs and cats presenting as bilateral hypointensity on T2w and iron-sensitive MRI sequences (SWI, T2*). [PDF]
Fischer C +5 more
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Increased iron deposition in putamen and substantia nigra correlates with cognitive function in cerebral small vessel disease: A quantitative susceptibility mapping study. [PDF]
Feng M +7 more
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Unraveling the complexity of neurodegeneration: heterogeneous damage patterns of locus coeruleus and substantia nigra in Alzheimer's disease. [PDF]
Tang C +6 more
europepmc +1 more source
Spatiotemporal changes in substantia nigra neuromelanin content in Parkinson’s disease [PDF]
International audienceAbstract This study aimed to investigate the spatiotemporal changes in neuromelanin-sensitive MRI signal in the substantia nigra and their relation to clinical scores of disease severity in patients with early or progressing ...
Emma Biondetti +2 more
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Substantia Nigra and Parkinsonism
Archives of Neurology, 1964The opinion that parkinsonism is caused by damage of the substantia nigra was advanced by Brissaud 1 on the basis of the findings in a case of Charcot's studied by Bechet 2 and Blocq and Marinesco. 3 In a series of 54 autopsies Tretiakoff 4 found the substantia nigra degenerated in 16 categories of neurologic disorder including three cases of ...
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Innervation of the substantia nigra
Cell and Tissue Research, 2004This review describes inputs to neurons in the substantia nigra and contrasts them with the action of agonists for the putative receptors through which they act. Special emphasis is placed on gamma-aminobutyric acid (GABA) afferents. Dopamine released from the somato-dendritic compartment of dopamine neurons and endocannabinoids released from dopamine ...
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Neuropathology of the Substantia nigra
European Neurology, 2008Neuronal subpopulations of the substantia nigra pars compacta can be separated into two functionally distinct nigrostriatal projections, the ventral tier which is poorly melanised, and the dorsal tier which is well melanised. In Parkinson’s disease, juvenile-onset parkinsonism with dystonia and striatonigral degeneration the ventral tier is more ...
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