Results 221 to 230 of about 86,799 (302)

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

Mass Spectrometry Reviews, Volume 45, Issue 4, Page 599-623, July/August 2026.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Neuromelanin Contrast Optimization and Improved Visualization of the Substantia Nigra in a 3D Gradient-Echo Sequence With Magnetization Transfer. [PDF]

NMR Biomed
Andikoetxea BG, Martín-Bastida A, Vidorreta M, Rodríguez-Oroz MC, Soustelle L, Troalen T, Fernández-Seara MA.   +6 more
europepmc   +1 more source

Does Resistance Training Improve the Quality of Life of People With Parkinson's Disease? Evidence and Recommendations for Clinical Application Through a Systematic Review and Meta‐Analysis of Randomized Clinical Trials

Physiotherapy Research International, Volume 31, Issue 3, July 2026.
ABSTRACT Background Parkinson's disease is a neurological condition with motor and non‐motor symptoms that negatively affect well‐being and quality of life. Objective This review aimed to analyze the effects of resistance training on quality of life in individuals with Parkinson's disease and to summarize recommendations for clinical application.
Loiane Cristina de Souza, Luiz Senna, Anderson D'Oliveira, Rubia Truppel, Guilherme Torres Vilarino, Alexandro Andrade   +5 more
wiley   +1 more source

Glial cell-specific proteomic data from the substantia nigra of a rat 6-OHDA and fluorocitrate model of astrocyte death and microglial activation. [PDF]

Data Brief
Kadłuczka J, Chubukova T, Mielczarek P, Maziak A, Roman A, Napieralska E, Kuter KZ.   +6 more
europepmc   +1 more source

The Effect of Dopaminergic Medication on Impulse Control and Compulsive Behaviour: A Translational Perspective

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT Dopaminergic medication used in disorders like Parkinson's disease (PD) and restless legs syndrome can cause impulsive‐compulsive behaviour (ICB), often with strong negative effects on patients' quality of life. This narrative review presents translational evidence on iatrogenic ICB, taking findings from epidemiological, clinical, neuroimaging
Mirjam Wolfschlag, Elena Espa, Kevin Oliveira Hauer, Jonathan Timpka, Ruben Smith, Per Odin, Maria Angela Cenci, Anders Håkansson   +7 more
wiley   +1 more source

Distinct regional patterns of synaptic vulnerability across hippocampal and parahippocampal subregions in Alzheimer's disease

Brain Pathology, Volume 36, Issue 4, July 2026.
Synaptic loss in Alzheimer's disease predominantly affects the entorhinal cortex and parahippocampal gyrus. Amyloid‐β and p‐tau pathology show global associations with synaptic density but are limited in specific subregions. Instead, axonal damage associates with synaptic loss locally and in interconnected subregions.
Maud M. A. Bouwman, Irene Frigerio, Yvon Galis‐de Graaf, Wilma D. J. van de Berg, Laura E. Jonkman   +4 more
wiley   +1 more source

The Discovery of Phages in the Substantia Nigra and Its Implication for Parkinson's Disease. [PDF]

Research (Wash D C)
Zhao Y, Xiong C, Wang B, Li D, Liu J, Wei S, Hou Y, Zhou Y, Zheng R.   +8 more
europepmc   +1 more source

Freezing of Gait Levodopa Response Pattern in Parkinson's Disease Provides Clues to Pathophysiology

European Journal of Neuroscience, Volume 64, Issue 1, July 2026.
ABSTRACT Freezing of gait (FOG) is a common and enigmatic feature of Parkinson's disease (PD) because of its episodic and unpredictable nature. It is now clear that FOG is not a monolithic phenomenon but instead exhibits substantial heterogeneity across patients, suggesting the existence of subtypes.
Stewart A. Factor, David Weinshenker, Jeanne Powell, Andrew S. Monaghan, Daniel S. Peterson, J. Lucas Mckay   +5 more
wiley   +1 more source