Results 201 to 210 of about 86,799 (302)

Restoring failed inhibition in the substantia nigra pars reticulata suppresses absence seizures in rats. [PDF]

Epilepsia
Palmer D, Forcelli PA.
europepmc   +1 more source

Frontotemporal Lobar Degeneration‐TDP Type C With Striatal Glial Cytoplasmic Inclusions and Motor Neuron Degeneration

Neuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
We report an autopsy case of frontotemporal lobar degeneration (FTLD)‐TDP type C with severe striatal involvement and annexin A11‐ and phosphorylated TDP‐43‐positive glial cytoplasmic inclusions. The patient developed progressive asymmetric rigidity accompanied by marked striatal atrophy and showed both upper and lower motor neuron involvement.
Akiko Uchino, Kazutomi Kanemaru, Airi Tarutani, Masato Hasegawa, Hiroya Naruse, Hiroyuki Ishiura, Shigeo Murayama, Yuko Saito   +7 more
wiley   +1 more source

Substantia nigra-related gene polymorphisms associated with acute antipsychotic-induced movement disorders. [PDF]

Mil Med Res
Hashimoto K.
europepmc   +1 more source

Chronic pruritus treated with alendronate in bilateral striopallidodentate calcinosis associated with an SLC20A2 gene mutation

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Adrien Boyard, Florian Stéphan, Boris Chaumette, Mathilde Moreau, Laure Bleton, Nicolas Hornez, Steeve Genestet, Jérémy Betrand, Amélie Bourhis, Morgane Le Bon‐Jégo, Thierry Bienvenu, Camille Verebi, Laurent Misery   +12 more
wiley   +1 more source

Protein Disulfide Isomerase Disassembles TDP‐43/G3BP1 Condensates and Antagonizes TDP‐43 Pathological Aggregates

Advanced Science, Volume 13, Issue 38, 9 July 2026.
Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu, Hao Liu, Yu‐Xuan Sun, Yuying Li, Xiangyi Liu, Li‐Qiang Wang, Zhaofei Yang, Qi Fu, Xiaojiao Xu, Jie Chen, Yingshuang Zhang, Jun Zhou, Weidong Le, Mengchao Cui, Yi Liang   +14 more
wiley   +1 more source

Japanese Encephalitis: Characteristic Imaging in Substantia Nigra, Thalamus, and Basal Ganglia. [PDF]

Intern Med
Sekiguchi K, Sawada J, Anan Y, Fujimoto S.   +3 more
europepmc   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, Volume 13, Issue 37, 3 July 2026.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

The spatial landscape of glial pathology and T cell response in Parkinson's disease substantia nigra. [PDF]

Nat Commun
Ma M, Paryani F, Jakubiak K, Xia S, Antoku S, Kannan A, Lee J, Madden N, Senthil Kumar S, Li J, Chen D, Hargus G, Mahajan A, Flowers X, Harms AS, Sulzer D, Goldman JE, Sims PA, Al-Dalahmah O.   +18 more
europepmc   +1 more source

Postmortem brain MRI reveals differential associations of subcortical and limbic volumes with cortical thinning and neurodegenerative pathologies

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION The impact of different neuropathologies on deep brain structures remains to be understood. We examine subcortical and limbic volumetry in neurodegenerative diseases involving phosphorylated tau (p‐tau), α‐synuclein, and transactive response DNA binding protein 43 (TDP‐43).
Pulkit Khandelwal, Michael Tran Duong, Lisa M. Levorse, Winifred Trotman, Alejandra Bahena, Sydney A. Lim, Amanda E. Denning, Eunice Chung, Christopher A. Olm, Hamsanandini Radhakrishnan, Ranjit Ittyerah, Karthik Prabhakaran, Gabor Mizsei, Theresa Schuck, Sheina Emrani, Joaquin A. Vizcarra, John Robinson, Daniel T. Ohm, Jeffrey S. Phillips, Jesse Cohen, Laura E. M. Wisse, John A. Detre, Ilya M. Nasrallah, Christopher A. Brown, Sandhitsu R. Das, Edward B. Lee, M. Dylan Tisdall, David J. Irwin, Corey T. McMillan, David A. Wolk, Paul A. Yushkevich   +30 more
wiley   +1 more source

Substantia nigra pars reticulata involvement in auditory hallucinations of treatment-resistant schizophrenia: a deep brain stimulation case report. [PDF]

Schizophrenia (Heidelb)
Shen A, Salimpour Y, Butala A, Kim MJ, Choi KS, Bray M, Nucifora F, Schretlen D, Harvey P, Anderson WS, Figee M, Mills KA, Sawa A, Cascella NG.   +13 more
europepmc   +1 more source