Results 211 to 220 of about 134,010 (347)

Schedule‐dependent neuroprotection by pioglitazone in a novel model of α‐synucleinopathy in rats: Integrated behavioural and histological outcomes

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda   +5 more
wiley   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study. [PDF]

open access: yesAdv Biol (Weinh)
Eggers B   +10 more
europepmc   +1 more source

Amylin analogues as a novel perspective in anti‐obesity therapy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Public health systems face a major challenge because of the worldwide obesity epidemic. The number of obese individuals has increased dramatically and, even in Switzerland which may be considered a relatively “lean” country, the numbers are alarmingly high and have reached almost 50% of the adult population.
Thomas A. Lutz
wiley   +1 more source

Next‐Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS

open access: yesCell Proliferation, EarlyView.
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang   +8 more
wiley   +1 more source

Dopamine D1 Receptor Immunoreactivity on Fine Processes of GFAP-Positive Astrocytes in the Substantia Nigra Pars Reticulata of Adult Mouse [PDF]

open access: gold, 2017
Katsuhiro Nagatomo   +6 more
openalex   +1 more source

The influence of motor and non‐motor characteristics of Parkinson's disease on motor imagery vividness

open access: yesJournal of Neuropsychology, EarlyView.
Abstract Motor imagery (MI) can facilitate movement in healthy individuals and patient populations. People with Parkinson's (PwP) experience debilitating motor symptoms, yet appear to have relatively intact MI capabilities, which may position MI as an effective therapeutic adjunct to existing interventions for PwP.
Camilla Woodrow‐Hill   +5 more
wiley   +1 more source

Substantia nigra pars reticulata involvement in auditory hallucinations of treatment-resistant schizophrenia: a deep brain stimulation case report. [PDF]

open access: yesSchizophrenia (Heidelb)
Shen A   +13 more
europepmc   +1 more source

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