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Culture of Substantia Nigra Neurons
Current Protocols in Neuroscience, 1997AbstractPrimary cultures of nigral tissue are widely used as a model system to assay effects of trophic and toxic agents on dopaminergic neurons. Cultured dopaminergic neurons have been successfully transplanted in animals and led to behavioral improvement in animal models of Parkinson's disease.
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The striatum and substantia nigra: A commentary on their relationships
Neuroscience, 1979Publisher Summary The greatest focus of attention in recent years regarding the functions of the basal ganglia has been given to examining the interrelationships between the striatum (caudate and putamen) and the substantia nigra . These structures, like others of the basal ganglia, are involved in the control of posture and locomotion, the ...
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Increased free water in the substantia nigra in idiopathic REM sleep behaviour disorder
Brain, 2021Ming Zhang, Guanyu Ye
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Spatiotemporal changes in substantia nigra neuromelanin content in Parkinson’s disease
Brain, 2020Emma Biondetti +2 more
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