Results 251 to 260 of about 133,054 (344)

Expression of Genes Encoding Receptors for Classical Neurotransmitters, Neuropeptides and Hormones in the Substantia Nigra, Especially in Dopaminergic Neurons, in Intact Mice and Mouse Models of Parkinson's Disease. [PDF]

Cells
Troshev D, Pavlova E, Bogdanov V, Ugrumov M.   +3 more
europepmc   +1 more source

Patient Agitation in the Intensive Care Unit: A Concept Analysis

Journal of Advanced Nursing, Volume 82, Issue 2, Page 1737-1749, February 2026.
ABSTRACT Aim Exploring the concept of patient agitation in the intensive care unit. Background Patient agitation in the intensive care unit is of widespread concern and linked to negative outcomes for patients, staff, and family members. There is currently no consensus on what constitutes agitation in the intensive care context, hindering effective and
Anne Mette N. Adams, Diane Chamberlain, Charlotte Brun Thorup, Matthew J. Maiden, Cherie Waite, Hila Ariela Dafny, Kay Bruce, Tiffany Conroy   +7 more
wiley   +1 more source

Autologous Peripheral Nerve Tissue Grafts Implanted into the Nucleus Basalis of Meynert and Substantia Nigra at the Time of Bilateral Deep Brain Stimulation in Parkinson Disease: A Report of 2 Cases. [PDF]

Neurosurg Pract
Daly SR, Quintero JE, Koehl L, Wallace E, Guduru Z, Gurwell JA, Hines T, Hixson J, Hulou S, Slevin JT, Schmitt FA, Gerhardt GA, van Horne CG.   +12 more
europepmc   +1 more source

Purkinje Cell Loss in Essential Tremor: Collective Data From 215 Brains Over a 21‐Year Period

Annals of Clinical and Translational Neurology, Volume 13, Issue 1, Page 36-48, January 2026.
ABSTRACT Objective Essential tremor is a highly prevalent movement disorder. Pathological changes observed in essential tremor cerebella center around Purkinje cells and neighboring neuronal populations. Postmortem studies have variably, but not always, shown reduced Purkinje cell counts in essential tremor compared to controls.
Chloë A. Kerridge, Roberto S. Hernandez, Nora C. Hernandez, Phyllis L. Faust, Elan D. Louis   +4 more
wiley   +1 more source

The effect of cannabinoid type Ⅱ receptor on the excitability of substantia nigra dopaminergic neurons. [PDF]

Front Pharmacol
Zhao S, Liu S, Gong Y, Ma Z.
europepmc   +1 more source

High-Intensity Exercise Acutely Increases Substantia Nigra and Prefrontal Brain Activity in Parkinson’s Disease

, 2017
Neil Kelly, Kimberly H. Wood, Jane B. Allendorfer, Matthew P. Ford, C. Scott Bickel, Jon Marstrander, Amy W. Amara, Thomas Anthony, Marcas M. Bamman, Frank M. Skidmore   +9 more
openalex   +2 more sources

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang, Tsering Yangzom, Ning Lu, Shenglong Deng, Xianglu Xiao, Guang Yang, Kristina Xiao Liang   +6 more
wiley   +1 more source

High-resolution mapping of substantia nigra in Parkinson's disease using 7 tesla magnetic resonance imaging. [PDF]

NPJ Parkinsons Dis
Madelung CF, Løkkegaard A, Fuglsang SA, Marques MM, Boer VO, Madsen KH, Hejl AM, Meder D, Siebner HR.   +8 more
europepmc   +1 more source

Associations between metabolic syndrome and regional brain iron depositions and cognitive function in middle‐aged and older adults: A two multinational cohort study

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION The alterations of regional brain iron in patients with metabolic syndrome (Mets) and its relationship with cognitive function remain unclear. METHODS These analyses utilized data from two prospective cohorts, from the UK Biobank (UKB) (21,346 participants) and from Jinan, China (224 participants). We capitalized brain iron in the
Xinyue Zhang, Linfeng Yang, Na Wang, Yuanyuan Wang, Qihao Zhang, Zhenyu Cheng, Yiwen Chen, Pengcheng Liang, Meng Li, Lingfei Guo, Changhu Liang   +10 more
wiley   +1 more source

Multi-neuromeric origin of tyrosine hydroxylase-positive neurons within the substantia nigra and ventral tegmental area. [PDF]

Front Neuroanat
Ferran JL, Lucero-Arteaga F, Ayad A, Kutsenko Y, Alonso A, Do-Couto BR, García-Cabezas MÁ, Tseng KY.   +7 more
europepmc   +1 more source