New MRI diagnostic methods in Parkinson's disease: evaluating nigral degeneration
Анналы клинической и экспериментальной неврологии, 2019 Research Center of Neurology, Moscow, Russia Parkinson's disease (PD) is a progressive neurodegenerative disorder with a characteristic pathological hallmark of loss of the dopaminergic neurons in the compact part of the substantia nigra in the ...
Sergey N. Illarioshkin +3 more
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Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases
Annals of Neurology, EarlyView.Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich +20 more
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Beitrag zur vergleichenden Anatomie der Substantia nigra, des Corpus Luysii und der Zona incerta. (Fortsetzung.) [PDF]
, 1910 Torata Sano
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Diffusion Kurtosis Imaging for Detection of Early Brain Changes in Parkinson's Disease
Frontiers in Neurology, 2019 We aimed to evaluate microscale changes in the bilateral red nucleus and substantia nigra of patients with Parkinson's disease (PD) using diffusion kurtosis imaging (DKI).
Jitian Guan +17 more
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What does it mean? Translating anatomical language to engage public audiences
Anatomical Sciences Education, EarlyView.Abstract The language of anatomy, with its roots in Ancient Greek and Roman languages, is complex and unfamiliar to many. Its complexity creates a significant barrier to public knowledge and understanding of anatomy—many members of the public find themselves asking “what does it mean?”, and this can manifest as poor health literacy and outcomes.
Kat A. Sanders, Adam M. Taylor
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Cell Transplantation, 1999 Current clinical protocols for fetal cell transplantation for Parkinson's disease (PD) have focused on restoring dopamine in the striatum. However, there are now a number of human transplant recipients who have had robust innervation of the striatum by ...
Philip A. Starr M.D.,Ph.D. +3 more
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A Local Circuit Model of Learned Striatal and Dopamine Cell Responses under Probabilistic Schedules of Reward [PDF]
, 2007 Before choosing, it helps to know both the expected value signaled by a predictive cue and the associated uncertainty that the reward will be forthcoming. Recently, Fiorillo et al.
Bullock, Daniel, Tan, Can Ozan
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Learning Contextual Reward Expectations for Value Adaptation [PDF]
, 2018 Substantial evidence indicates that subjective value is adapted to the statistics of reward expected within a given temporal context. However, how these contextual expectations are learned is poorly understood.
Chew, B. +3 more
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Autism Research, EarlyView.ABSTRACT Emerging evidence highlights widespread alterations in white matter microstructure in autism. Advances in magnetic resonance imaging (MRI) have enabled more precise examinations of these microstructural changes, leading to increased use of quantitative MRI techniques in autism research.
Christy D. Yoon, Douglas C. Dean III
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Effect of ghrelin gene knockout on the postsynaptic potential of dopaminergic neurons in the substantia nigra of mice [PDF]
精准医学杂志Objective To study the effect of ghrelin gene knockout on the postsynaptic potential of dopaminergic neurons in the substantia nigra of mice. Methods Substantia nigra tissue was taken from 10-week-old ghrelin-/- male mice (ghrelin-/- group) and their ...
LIU Jing, LI Huanhuan, JIAO Qian, CHEN Xi, JIANG Hong, DU Xixun
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