Results 71 to 80 of about 71,981 (295)

OXIDATIVE STRESS-DEPENDENT ALTERED IMMUNE RESPONSES AND CELL DEATH IN SUBSTANTIA NIGRA AFTER OZONE EXPOSURE IN RAT

Frontiers in Aging Neuroscience, 2015
Parkinson’s disease has been associated with the selective loss of neurons in the substantia nigra pars compacta. Increasing evidence suggests that oxidative stress plays a major role. The resulting increase in reactive oxygen species triggers a sequence
Selva eRivas - Arancibia, Luis Fernando Hernandez - Zimbron, Ana Erika Rodriguez - Martinez, Perla eDeyanira-Maldonado, Gabino eBorgonio - Perez, Maria eSepulveda - Parada   +5 more
doaj   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

The action of muscimol on neurones of the substantia nigra of the rat [PDF]

, 1978
H.-R. Olpe, Werner P. Koella
openalex   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

Exploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang, Ying Liu, Xiadong Zhu, Lizhen He, Tianfeng Chen   +4 more
wiley   +1 more source

Epigenetic insights into neuropsychiatric and cognitive symptoms in Parkinson’s disease: A DNA co-methylation network analysis

npj Parkinson's Disease
Parkinson’s disease is a highly heterogeneous disorder, encompassing a complex spectrum of clinical presentation including motor, sleep, cognitive and neuropsychiatric symptoms.
Joshua Harvey, Adam R. Smith, Luke S. Weymouth, Rebecca G. Smith, Isabel Castanho, Leon Hubbard, Byron Creese, Catherine Bresner, Nigel Williams, Ehsan Pishva, Katie Lunnon   +10 more
doaj   +1 more source

The substantia nigra in Parkinsonism. [PDF]

Journal of Clinical Pathology, 1969
S. Roy, L Wolman
openaire   +3 more sources

Phytochemistry, pharmacological insights, and food science applications of natural bioactive compounds from Ocimum species with a focus on essential oils

Food Frontiers, EarlyView.
The article examines the phytochemistry, pharmacology, and food science applications of essential oils and extracts from Ocimum species (basil). It covers diverse extraction methods like hydrodistillation and microwave‐assisted extraction while discussing pharmacological benefits.
Oberdan Oliveira Ferreira, Ravendra Kumar, Luiz Renan Ramos da Silva, Suraj N. Mali, Srushti Tambe, Ulisses Alves Rosa, Leonardo Souza Costa, Lohren Glendha Nunes Lobato, Anderson de Santana Botelho, Himani Karakoti, Sonu Kumar Mahawer, Marcilene Paiva da Silva, Mozaniel Santana de Oliveira, Eloisa Helena de Andrade Aguiar   +13 more
wiley   +1 more source

Progress of non‐motor symptoms in early‐onset Parkinson's disease

Ibrain, EarlyView.
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang, Aidi Luo, Shusheng Liao, Mei Liu, Jun Zhang, Zucai Xu   +5 more
wiley   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Neuroinflammation drives apathy in cancer cachexia

Cancer Communications, EarlyView.
Bingjun Ha, Xuetao Cao
wiley   +1 more source