Results 1 to 10 of about 10,527,966 (376)

SUBSTRATE SPECIFICITY OF AMINE OXIDASE [PDF]

, 1943
The tyramine oxidase activity of liver extracts found by Hare (1), the aliphatic amine oxidase activity of brain, kidney, and liver extracts observed by Pugh and Quastel (2), and the adrenalin oxidase activity of similar extracts noted by Blaschko ...
Gordon A. Alles, Erik Heegaard
openalex   +3 more sources

Structural basis of SIRT7 nucleosome engagement and substrate specificity [PDF]

Nature Communications
Chromatin-modifying enzymes target distinct residues within histones to finetune gene expression profiles. SIRT7 is an NAD+-dependent deacylase often deregulated in cancer, which deacetylates either H3 lysine 36 (H3K36) or H3K18 with high specificity ...
Carlos Moreno-Yruela, Babatunde E. Ekundayo, Polina N. Foteva, Dongchun Ni, Esther Calvino-Sanles, Henning Stahlberg, Beat Fierz   +6 more
doaj   +3 more sources

Discovery and substrate specificity engineering of nucleotide halogenases [PDF]

Nature Communications
C2′-halogenation has been recognized as an essential modification to enhance the drug-like properties of nucleotide analogs. The direct C2ʹ-halogenation of the nucleotide 2′-deoxyadenosine-5′-monophosphate (dAMP) has recently been achieved using the Fe ...
Jie Ni, Jingyuan Zhuang, Yiming Shi, Ying-Chih Chiang, Gui-Juan Cheng   +4 more
doaj   +2 more sources

Structural Analysis and Substrate Specificity of D-Carbamoylase from Pseudomonas [PDF]

BioTech
The synthesis of enantiomeric forms of D-amino acids can be achieved by a two-step “hydantoinase process” based on the sequential catalysis of substrates by specific enzymes, D-carbamoylase and D-hydantoinase. Here, we describe the structural features of
Marina Paronyan, Haykanush Koloyan, Hovsep Aganyants, Artur Hambardzumyan, Tigran Soghomonyan, Sona Avetisyan, Sergey Kocharov, Henry Panosyan, Vehary Sakanyan, Anichka Hovsepyan   +9 more
doaj   +2 more sources

Substrate Specificity of Hexokinases

Journal of Biological Chemistry, 1961
Charles F. Lange, Paul M. Kohn
openalex   +4 more sources

Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase

Viruses, 2021
The ongoing COVID-19 pandemic exemplifies the general need to better understand viral infections. The positive single-strand RNA genome of its causative agent, the SARS coronavirus 2 (SARS-CoV-2), encodes all viral enzymes.
Roberto Benoni, Petra Krafcikova, Marek R. Baranowski, Joanna Kowalska, Evzen Boura, Hana Cahová   +5 more
doaj   +1 more source

L1CAM binds ErbB receptors through Ig-like domains coupling cell adhesion and neuregulin signalling. [PDF]

, 2012
During nervous system development different cell-to-cell communication mechanisms operate in parallel guiding migrating neurons and growing axons to generate complex arrays of neural circuits.
Baars, S, Cabedo, H, Donier, E, Garcia-Alonso, L, Gomez-Sanchez, JA, Grijota-Martinez, C, Lakomá, J   +6 more
core   +9 more sources

Profiling of substrate specificity of SARS-CoV 3CL. [PDF]

PLoS ONE, 2010
BACKGROUND: The 3C-like protease (3CL(pro)) of severe acute respiratory syndrome-coronavirus is required for autoprocessing of the polyprotein, and is a potential target for treating coronaviral infection.
Chi-Pang Chuck, Lin-Tat Chong, Chao Chen, Hak-Fun Chow, David Chi-Cheong Wan, Kam-Bo Wong   +5 more
doaj   +1 more source

The Substrate Specificity of Pantethinase [PDF]

European Journal of Biochemistry, 1973
The substrate specificty of pantethinase, the mammalian enzyme which has been isolated from horse kidney cortex, has been studied. The real substrate has been found to be pantetheine in the reduced form, and the involvement of one or more—SH groups of the enzyme is also considered.A number of other compounds, chemically related to pantetheine, has also
Rosei Ma, Luisa Bellussi, Elena Del Grosso, Doriano Cavallini, Silvestro Duprè   +4 more
openaire   +3 more sources

Tocopherol Cyclases-Substrate Specificity and Phylogenetic Relations. [PDF]

PLoS ONE, 2016
In the present studies, we focused on substrate specificity of tocopherol cyclase, the key enzyme in the biosynthesis of the tocopherols and plastochromanol-8, the main plant lipid antioxidants, with special emphasis on the preference for tocopherols and
Jolanta Dłużewska, Renata Szymańska, Michal Gabruk, Peter B Kós, Beatrycze Nowicka, Jerzy Kruk   +5 more
doaj   +1 more source