Results 1 to 10 of about 10,376,430 (391)
Substrate specificity of amine oxidase [PDF]
, 1943 The tyramine oxidase activity of liver extracts found by Hare (1), the aliphatic amine oxidase activity of brain, kidney, and liver extracts observed by Pugh and Quastel (2), and the adrenalin oxidase activity of similar extracts noted by Blaschko ...
Alles, Gordon A., Heegaard, Erik V.
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Structural basis of SIRT7 nucleosome engagement and substrate specificity [PDF]
Nature CommunicationsChromatin-modifying enzymes target distinct residues within histones to finetune gene expression profiles. SIRT7 is an NAD+-dependent deacylase often deregulated in cancer, which deacetylates either H3 lysine 36 (H3K36) or H3K18 with high specificity ...
Carlos Moreno-Yruela +6 more
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Discovery and substrate specificity engineering of nucleotide halogenases [PDF]
Nature CommunicationsC2′-halogenation has been recognized as an essential modification to enhance the drug-like properties of nucleotide analogs. The direct C2ʹ-halogenation of the nucleotide 2′-deoxyadenosine-5′-monophosphate (dAMP) has recently been achieved using the Fe ...
Jie Ni +4 more
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Structural Analysis and Substrate Specificity of D-Carbamoylase from Pseudomonas [PDF]
BioTechThe synthesis of enantiomeric forms of D-amino acids can be achieved by a two-step “hydantoinase process” based on the sequential catalysis of substrates by specific enzymes, D-carbamoylase and D-hydantoinase. Here, we describe the structural features of
Marina Paronyan +9 more
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Substrate specificity mapping of fungal CAZy AA3_2 oxidoreductases [PDF]
Biotechnology for Biofuels and BioproductsBackground Oxidative enzymes targeting lignocellulosic substrates are presently classified into various auxiliary activity (AA) families within the carbohydrate-active enzyme (CAZy) database.
Hongbo Zhao +9 more
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Substrate Specificity of Hexokinases
Journal of Biological Chemistry, 1961 Charles F. Lange, Paul Kohn
openaire +4 more sources
Substrate Specificity of SARS-CoV-2 Nsp10-Nsp16 Methyltransferase
Viruses, 2021 The ongoing COVID-19 pandemic exemplifies the general need to better understand viral infections. The positive single-strand RNA genome of its causative agent, the SARS coronavirus 2 (SARS-CoV-2), encodes all viral enzymes.
Roberto Benoni +5 more
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Profiling of substrate specificity of SARS-CoV 3CL. [PDF]
PLoS ONE, 2010 BACKGROUND: The 3C-like protease (3CL(pro)) of severe acute respiratory syndrome-coronavirus is required for autoprocessing of the polyprotein, and is a potential target for treating coronaviral infection.
Chi-Pang Chuck +5 more
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The Substrate Specificity of Pantethinase [PDF]
European Journal of Biochemistry, 1973 The substrate specificty of pantethinase, the mammalian enzyme which has been isolated from horse kidney cortex, has been studied. The real substrate has been found to be pantetheine in the reduced form, and the involvement of one or more—SH groups of the enzyme is also considered.A number of other compounds, chemically related to pantetheine, has also
Rosei Ma +4 more
openaire +3 more sources
Probing ADAMTS13 substrate specificity using phage display. [PDF]
PLoS ONE, 2015 Von Willebrand factor (VWF) is a large, multimeric protein that regulates hemostasis by tethering platelets to the subendothelial matrix at sites of vascular damage.
Karl C Desch +7 more
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