Results 21 to 30 of about 453,916 (245)
Substrate Specificity of Chlorophyllase [PDF]
Plant Physiology, 1975 Apparent Km and V(max) values were obtained for hydrolysis of methyl and ethyl chlorophyllides a, methyl and ethyl pheophorbide a, and 9-hydroxymethyl pheophorbide a by chlorophyllase from Ailanthus altissima. Analysis of substrate specificity data for chlorophyllase indicates that the presence of a 9-keto group and a methyl alcohol group esterified at
openaire +2 more sources
On the substrate specificity of human CYP27A1
Journal of Lipid Research, 2003 The mitochondrial sterol 27-hydroxylase (CYP27A1) is required for degradation of the C27-sterol side chain in bile acid biosynthesis. CYP27A1 seems, however, to have roles beyond this, as illustrated by patients with a deficient sterol 27-hydroxylase due
Maria Norlin +3 more
doaj +1 more source
Biomolecules, 2022 Jumonji C (JmjC) lysine demethylases (KDMs) catalyze the removal of methyl (-CH3) groups from modified lysyl residues. Several JmjC KDMs promote cancerous properties and these findings have primarily been in relation to histone demethylation.
Anand Chopra +2 more
doaj +1 more source
Substrate specificity of Ty1 integrase [PDF]
Journal of Virology, 1995 Integration of the Saccharomyces cerevisiae retrotransposon Ty1 requires the element-encoded integrase (IN) protein, which is a component of cytoplasmic virus-like particles (VLPs). Using purified recombinant Ty1 IN and an oligonucleotide integration assay based on Ty1 long terminal repeat sequences, we have compared IN activity on substrates having ...
S P, Moore, M, Powers, D J, Garfinkel
openaire +2 more sources
Elucidation of substrate specificity in Aspergillus nidulans UDP-galactose-4-epimerase. [PDF]
PLoS ONE, 2013 The frequency of invasive fungal infections has rapidly increased in recent years. Current clinical treatments are experiencing decreased potency due to severe host toxicity and the emergence of fungal drug resistance.
Sean A Dalrymple +4 more
doaj +1 more source
Substrate specificity of the cypemycin decarboxylase CypD
Synthetic and Systems Biotechnology, 2018 The linaridin antibiotic cypemycin is a ribosomal synthesized and post-translationally modified peptide (RiPP) that possesses potent activity against mouse leukemia cells.
Wei Ding +3 more
doaj +1 more source
Journal of Lipid Research, 1993 In this study we used monoacid triacylglycerols of various acyl-chain lengths as substrates for probing the active-site structure and substrate specificity of lipoprotein lipase (LPL).
Chi-Sun Wang +3 more
doaj +1 more source
Substrate specificity of the TRAMP nuclear surveillance complexes
Nature Communications, 2020 During nuclear surveillance in yeast and human cells, the RNA exosome functions together with the TRAMP complexes. Here, the authors defined the protein composition of the TRAMP complexes and identified specific RNA binding sites for the different TRAMP ...
Clémentine Delan-Forino +3 more
doaj +1 more source
Substrate specificity of prostate-specific antigen (PSA)
Chemistry & Biology, 1998 The serine protease prostate-specific antigen (PSA) is a useful clinical marker for prostatic malignancy. PSA is a member of the kallikrein subgroup of the (chymo)trypsin serine protease family, but differs from the prototypical member of this subgroup, tissue kallikrein, in possessing a specificity more similar to that of chymotrypsin than trypsin. We
Coombs, Gary +8 more
openaire +2 more sources
The Substrate Specificity of Pantethinase [PDF]
European Journal of Biochemistry, 1973 The substrate specificty of pantethinase, the mammalian enzyme which has been isolated from horse kidney cortex, has been studied. The real substrate has been found to be pantetheine in the reduced form, and the involvement of one or more—SH groups of the enzyme is also considered.A number of other compounds, chemically related to pantetheine, has also
S, Duprè +4 more
openaire +2 more sources