Results 1 to 10 of about 38,288 (149)

Involvement of the subthalamic nucleus in impulse control disorders associated with Parkinson’s disease [PDF]

open access: yesBrain, 2011
Behavioural abnormalities such as impulse control disorders may develop when patients with Parkinson’s disease receive dopaminergic therapy, although they can be controlled by deep brain stimulation of the subthalamic nucleus.
Jon López-Azcárate   +2 more
exaly   +1 more source

The subthalamic nucleus : Part I: Development, cytology, topography and connections [PDF]

open access: yes, 2008
This monograph on the subthalamic nucleus accentuates in Part I the gap between experimental animal and human information concerning subthalamic development, cytology, topography and connections. The light and electron microscopical cytology concerns the
Heida, Tjitske   +3 more
core   +12 more sources

Dexmedetomidine depresses neuronal activity in the subthalamic nucleus during deep brain stimulation electrode implantation surgery

open access: yesBJA Open, 2022
Background: Micro-electrode recordings are often necessary during electrode implantation for deep brain stimulation of the subthalamic nucleus. Dexmedetomidine may be a useful sedative for these procedures, but there is limited information regarding its ...
Corey Amlong   +4 more
doaj   +1 more source

Sex modulates the outcome of subthalamic nucleus deep brain stimulation in patients with Parkinson’s disease

open access: yesNeural Regeneration Research, 2023
There are many documented sex differences in the clinical course, symptom expression profile, and treatment response of Parkinson’s disease, creating additional challenges for patient management.
Tian-Shuo Yuan   +7 more
doaj   +1 more source

Effects of bilateral subthalamic nucleus deep brain stimulation on motor symptoms in Parkinson’s disease: a retrospective cohort study

open access: yesNeural Regeneration Research, 2021
Deep brain stimulation of the bilateral subthalamic nucleus (STN) is a therapeutic option for patients with Parkinson’s disease (PD) in whom medical therapies have been ineffective.
Guo-Xiong Cheng   +6 more
doaj   +1 more source

Deep brain stimulation electrode position impact on parkinsonian non-motor symptoms

open access: yesBiomedical Papers, 2022
Background. In this study we evaluated the impact of location of deep brain stimulation electrode active contact in different parts of the subthalamic nucleus on improvement of non-motor symptoms in patients with Parkinson's disease. Methods.
Jan Bardon   +15 more
doaj   +1 more source

Subthalamic Nucleus Degeneration As A Dark Cause of Parkinson’s Disease Due to Subarachnoid Hemorrhage: A Preliminary Experimental Study

open access: yesJournal of Contemporary Medicine, 2023
Background: Although the subtahalamic nucleus degeneration has been accused of Parkinson’s disease, the obscure roles of subtalamic nucleus degeneration induced by subarachnoid hemorrhages has not been adequately studied.
Mehmet Hakan Şahin, Mete Zeynal
doaj   +1 more source

Brain tissue properties differentiate between motor and limbic basal ganglia circuits [PDF]

open access: yes, 2014
Despite advances in understanding basic organizational principles of the human basal ganglia, accurate in vivo assessment of their anatomical properties is essential to improve early diagnosis in disorders with corticosubcortical pathology and optimize ...
Accolla, EA   +10 more
core   +6 more sources

Dysconnectivity of the parafascicular nucleus in Parkinson's disease: A dynamic causal modeling analysis

open access: yesNeurobiology of Disease, 2023
Background: Recent animal model studies have suggested that the parafascicular nucleus has the potential to be an effective deep brain stimulation target for Parkinson's disease.
Lili Chen   +8 more
doaj   +1 more source

Impact of deep brain stimulation of the subthalamic nucleus on natural language in patients with Parkinson's disease.

open access: yesPLoS ONE, 2020
BackgroundIn addition to the typical motor symptoms, a majority of patients suffering from Parkinson's disease experience language impairments. Deep Brain Stimulation of the subthalamic nucleus robustly reduces motor dysfunction, but its impact on ...
Felicitas Ehlen   +3 more
doaj   +1 more source

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