Existing motor state is favored at the expense of new movement during 13-35 Hz oscillatory synchrony in the human corticospinal system [PDF]
Oscillations in local field potentials in the β-frequency band (13-35 Hz) are a pervasive feature of human and nonhuman primate motor cortical areas. However, the function of such synchronous activity across populations of neurons remains unknown.
B, B +6 more
core
Communication impairments in Parkinson's disease [PDF]
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Murdoch, Bruce +3 more
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Accurately describing the spiking patterns of neurons in the subthalamic nucleus of patients suffering from Parkinson’s disease is important for understanding the pathogenesis of the disease and for achieving the maximum therapeutic benefit from deep ...
Uri eEden +3 more
doaj +1 more source
Phase matters: A role for the subthalamic network during gait. [PDF]
The role of the subthalamic nucleus in human locomotion is unclear although relevant, given the troublesome management of gait disturbances with subthalamic deep brain stimulation in patients with Parkinson's disease.
Gabriele Arnulfo +9 more
doaj +1 more source
Towards a computational model for stimulation of the Pedunculopontine nucleus [PDF]
The pedunculopontine nucleus (PPN) has recently been suggested as a new therapeutic target for deep brain stimulation (DBS) in patients suffering from Parkinson's disease, particularly those with severe gait and postural impairment [1].
Gils, Stephan A. van +3 more
core +4 more sources
Weight gain is associated with medial contact site of subthalamic stimulation in Parkinson's disease. [PDF]
The aim of our study was to assess changes in body-weight in relation to active electrode contact position in the subthalamic nucleus. Regular body weight measurements were done in 20 patients with advanced Parkinson's disease within a period of 18 ...
Filip Růžička +5 more
doaj +1 more source
Cortical and Striatal Circuits in Huntington's Disease
Huntington's disease (HD) is a hereditary neurodegenerative disorder that typically manifests in midlife with motor, cognitive, and/or psychiatric symptoms.
Blumenstock, S., Dudanova, I.
core +1 more source
Functional MRI with active, fully implanted, deep brain stimulation systems: Safety and experimental confounds [PDF]
We investigated safety issues and potential experimental confounds when performing functional magnetic resonance imaging (fMRI) investigations in human subjects with fully implanted, active, deep brain stimulation (DBS) systems.
Allen, P.J. +7 more
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Subcortical correlates of consciousness with human single neuron recordings
Subcortical brain structures such as the subthalamic nucleus or the thalamus are involved in regulating motor and cognitive behavior. However, their contribution to perceptual consciousness remains unclear, due to the inherent difficulties of recording ...
Michael Pereira +10 more
doaj +1 more source
Acute hemiballismus in the absence of subthalamic nucleus lesion
A 68-year-old male, known hypertensive on irregular medication presented with sudden onset of involuntary movements of the left upper limb, in the form of severely violent, arrhythmic, and flinging large amplitude movements for 2 days, suggestive of ...
Shreya Gudi +2 more
doaj +1 more source

