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Architecture of the subthalamic nucleus [PDF]
Communications BiologyThe subthalamic nucleus (STN) is a major neuromodulation target for the alleviation of neurological and neuropsychiatric symptoms using deep brain stimulation (DBS). STN-DBS is today applied as treatment in Parkinson´s disease, dystonia, essential tremor,
Asheeta A. Prasad +1 more
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Unraveling the enigmatic role of the subthalamic nucleus [PDF]
eLifeSubpopulations of neurons in the subthalamic nucleus have distinct activity patterns that relate to the three hypotheses of the Drift Diffusion Model.
Qianli Yang
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Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease. [PDF]
New England Journal of Medicine, 2003 BACKGROUND Although the short-term benefits of bilateral stimulation of the subthalamic nucleus in patients with advanced Parkinson's disease have been well documented, the long-term outcomes of the procedure are unknown.
P. Krack +11 more
semanticscholar +6 more sources
Subthalamic Nucleus: Neuroanatomical Review [PDF]
Brazilian Neurosurgery, 2017 Discovered in 1865 by Jules Bernard Luys, the subthalamic nucleus is a set of small nuclei located in the diencephalon, inferior to the thalamus and superior to the substantia nigra, that can be visualized in a posterior coronal section.
Marcelo José Silva de Magalhães +9 more
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Pain in Parkinson's disease and the role of the subthalamic nucleus.
Brain, 2021 Pain is a frequent and poorly treated symptom of Parkinson's disease, mainly due to scarce knowledge of its basic mechanisms. In Parkinson's disease, deep brain stimulation of the subthalamic nucleus is a successful treatment of motor symptoms, but also ...
A. Mostofi +4 more
semanticscholar +5 more sources
Nature Communications, 2022 Chemogenetic inactivation of the subthalamic nucleus in monkeys increases spike train variability in the pallidum and prolongs movement time, suggesting its role in stabilizing pallidal spike trains to achieve stable motor control.
Taku Hasegawa +3 more
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Decisional impulsivity and the associative-limbic subthalamic nucleus in obsessive-compulsive disorder: stimulation and connectivity [PDF]
Brain : a journal of neurology, 2016 Why do we make hasty decisions for short-term gain? Rapid decision-making with limited accumulation of evidence and delay discounting are forms of decisional impulsivity.
V. Voon +7 more
semanticscholar +3 more sources
The subthalamic nucleus in the context of movement disorders [PDF]
Brain, 2003 The subthalamic nucleus (STN) has been regarded as an important modulator of basal ganglia output. It receives its major afferents from the cerebral cortex, thalamus, globus pallidus externus and brainstem, and projects mainly to both segments of the globus pallidus, substantia nigra, striatum and brainstem.
Clement Hamani
openalex +4 more sources
Are there three Subdivisions in the primate Subthalamic Nucleus? [PDF]
Frontiers in Neuroanatomy, 2012 The prevailing academic opinion holds that the subthalamic nucleus (STN) consists of three parts, each anatomically distinct and selectively associated with cognitive, emotional, or motor functioning.
Max C Keuken +7 more
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The subthalamic nucleus : Part I: Development, cytology, topography and connections [PDF]
, 2008 This monograph on the subthalamic nucleus accentuates in Part I the gap between experimental animal and human information concerning subthalamic development, cytology, topography and connections. The light and electron microscopical cytology concerns the
Heida, Tjitske +3 more
core +20 more sources