Results 111 to 120 of about 489,147 (319)
This study maps global trends in brain stimulation research for cognitive impairment using bibliometric analysis of 4156 records (1989–2024, WoSCC). Findings highlight the dominance of transcranial magnetic stimulation (TMS) and repetitive TMS (rTMS), emerging vascular‐focused research, and promising techniques like fast gamma magnetic stimulation and ...
Mani Abdul Karim
wiley +1 more source
Motor Evoked Potentials Improve Targeting in Deep Brain Stimulation Surgery
Abstract Objectives One of the main challenges posed by the surgical deep brain stimulation (DBS) procedure is the successful targeting of the structures of interest and avoidance of side effects, especially in asleep surgery. Here, intraoperative motor evoked potentials (MEPs) might serve as tool to identify the pyramidal tract.
Petyo Nikolov+7 more
wiley +1 more source
Dyskinesias and the subthalamic nucleus.
Severe dyskinesias or ballism can occur following hemorrhagic events in the subthalamic nucleus (STN), and it has recently been established that the STN plays a major role in the pathophysiology of the motor dysfunction of Parkinson's disease (PD) and that STN inhibition improves parkinsonian dysfunction.
Benabid, A L+6 more
openaire +2 more sources
Magnetic resonance imaging of the subthalamic nucleus for deep brain stimulation.
The subthalamic nucleus (STN) is one of the most important stereotactic targets in neurosurgery, and its accurate imaging is crucial. With improving MRI sequences there is impetus for direct targeting of the STN.
Arjun S. Chandran, M. Bynevelt, C. Lind
semanticscholar +1 more source
MR‐Guidance of Gene Therapy for Brain Diseases: Moving From Palliative Treatment to Cures
ABSTRACT Regulatory bodies in the U.S. and Europe recently approved a gene therapy for aromatic L‐amino acid decarboxylase (AADC) deficiency, a rare neurologic disorder where a genetic mutation prevents dopamine production in the brain. Affected children fail to develop normal motor and cognitive functions.
Dalton H. Bermudez+2 more
wiley +1 more source
Abstract Objective Published reports on directional deep brain stimulation (DBS) have been limited to small, single‐center investigations. Therapeutic window (TW) is used to describe the range of stimulation amplitudes achieving symptom relief without side effects.
Alfons Schnitzler+24 more
wiley +1 more source
Acute hemiballismus in the absence of subthalamic nucleus lesion
A 68-year-old male, known hypertensive on irregular medication presented with sudden onset of involuntary movements of the left upper limb, in the form of severely violent, arrhythmic, and flinging large amplitude movements for 2 days, suggestive of ...
Shreya Gudi+2 more
doaj +1 more source
Continuous Dice Coefficient: a Method for Evaluating Probabilistic Segmentations [PDF]
Objective: Overlapping measures are often utilized to quantify the similarity between two binary regions. However, modern segmentation algorithms output a probability or confidence map with continuous values in the zero-to-one interval. Moreover, these binary overlapping measures are biased to structure size.
arxiv
A selective role for ventromedial subthalamic nucleus in inhibitory control
The subthalamic nucleus (STN) is hypothesized to play a central role in the rapid stopping of movement in reaction to a stop signal. Single-unit recording evidence for such a role is sparse, however, and it remains uncertain how that role relates to the ...
B. Pasquereau, R. Turner
semanticscholar +1 more source
Abstract Objectives Obsessive–compulsive disorder (OCD) is a psychiatric disorder with alterations of cortico‐striato‐thalamo‐cortical loops and impaired performance monitoring. Electrophysiological markers such as conflict‐related medial frontal theta (MFT) and error‐related negativity (ERN) may be altered by clinically effective deep brain ...
Elena Sildatke+9 more
wiley +1 more source