Results 111 to 120 of about 502,362 (345)

A selective role for ventromedial subthalamic nucleus in inhibitory control

eLife, 2017
The subthalamic nucleus (STN) is hypothesized to play a central role in the rapid stopping of movement in reaction to a stop signal. Single-unit recording evidence for such a role is sparse, however, and it remains uncertain how that role relates to the ...
B. Pasquereau, R. Turner
semanticscholar   +1 more source

Efficacy and Safety of IncobotulinumtoxinA for Treatment of Sialorrhea: A Multicenter, Phase 3 Study in Japan

Movement Disorders Clinical Practice, EarlyView.
This study demonstrated significant treatment efficacy and safety of incobotulinumtoxinA injection in Japanese patients with chronic sialorrhea caused by Parkinson's disease and other neurological conditions. Suppression of salivary secretion and improvement in drooling symptoms were also observed throughout 48 weeks.
Nobutaka Hattori, Yohei Mukai, Noriko Nishikawa, Kazuko Hasegawa, Masahiko Tomiyama, Yasuyoshi Kimura, Yoshio Tsuboi, Ryosuke Takahashi, Ryota Nakamura, Yuishin Izumi, Hirohisa Watanabe, Morinobu Seki, Kenji Sekiguchi, Shohei Tateishi, Yusaku Matsushita, Yusaku Nakamura   +15 more
wiley   +1 more source

The Intraoperative Microlesion Effect Positively Correlates With the Short‐Term Clinical Effect of Deep Brain Stimulation in Parkinson's Disease

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical ...
Stèfan F. Lange, Naomi I. Kremer, Teus van Laar, Fiete Lange, T. Elien Steendam‐Oldekamp, D. L. Marinus Oterdoom, Anthony R. Absalom, J. Marc C. van Dijk, Gea Drost   +8 more
wiley   +1 more source

Molecular glucose imaging reveals functional brain reconfiguration by subthalamic deep brain stimulation in Parkinsonian rats

Translational Neurodegeneration
Background In order to elucidate the neuromodulatory mechanisms underlying therapeutic subthalamic deep brain stimulation (DBS), we here reverse-translate a methodological pipeline that integrates neurostimulation effect parameterization and molecular ...
Jiazhi Chen, Ningfei Li, Muthuraman Muthuraman, Nengxing Liang, Jens Volkmann, Takahiro Higuchi, Chi Wang Ip   +6 more
doaj   +1 more source

Subcortical correlates of consciousness with human single neuron recordings

eLife
Subcortical brain structures such as the subthalamic nucleus or the thalamus are involved in regulating motor and cognitive behavior. However, their contribution to perceptual consciousness remains unclear, due to the inherent difficulties of recording ...
Michael Pereira, Nathan Faivre, Fosco Bernasconi, Nicholas Brandmeir, Jacob E Suffridge, Kaylee Tran, Shuo Wang, Victor Finomore, Peter Konrad, Ali Rezai, Olaf Blanke   +10 more
doaj   +1 more source

Acute hemiballismus in the absence of subthalamic nucleus lesion

MGM Journal of Medical Sciences, 2020
A 68-year-old male, known hypertensive on irregular medication presented with sudden onset of involuntary movements of the left upper limb, in the form of severely violent, arrhythmic, and flinging large amplitude movements for 2 days, suggestive of ...
Shreya Gudi, Tushar Kanti Biswas, Rucha Sane   +2 more
doaj   +1 more source

A Combinatorial Solution to Non-Rigid 3D Shape-to-Image Matching [PDF]

, 2017
We propose a combinatorial solution for the problem of non-rigidly matching a 3D shape to 3D image data. To this end, we model the shape as a triangular mesh and allow each triangle of this mesh to be rigidly transformed to achieve a suitable matching to
Bernard, Florian, Cremers, Daniel, Schmidt, Frank R., Thunberg, Johan   +3 more
core   +2 more sources

Thalamic Deep Brain Stimulation for Dystonic Head Tremor: A Long‐Term Study of 18 Patients

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dystonic head tremor is a particular manifestation of dystonia, which is difficult to treat. Although deep brain stimulation (DBS) of the globus pallidus internus has been established as a treatment for different phenotypes of dystonia, its role in dystonic tremor has been debated.
Johanna M. Nagel, Marc E. Wolf, Christian Blahak, Joachim Runge, Christoph Schrader, Dirk Dressler, Assel Saryyeva, Joachim K. Krauss   +7 more
wiley   +1 more source

Effects of aging on nitrergic neurons in human striatum and subthalamic nucleus

Arquivos de Neuro-Psiquiatria, 2015
Nitric oxide (NO) is a major neurotransmitter associated with motor control in basal ganglia. Movement disorders, as essential tremor and Parkinson’s disease, are more prevalent on aged individuals.
Bruno Lopes dos Santos-Lobato, Elaine Aparecida Del-Bel, José Eymard Homem Pittella, Vitor Tumas   +3 more
doaj   +1 more source

Examining Device Usage Patterns in Outpatient Telemedicine Video Visits among Movement Disorders Patients

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Telemedicine has improved access to care, yet device usage for virtual visits remains underexplored. Objective To characterize device usage patterns for video televisits across sociodemographic factors in a tertiary Movement Disorders clinic in the United States.
Mitra Afshari, Vijay G. Palakuzhy, Bichun Ouyang, Glenn T. Stebbins, Christopher G. Goetz   +4 more
wiley   +1 more source